NPFFR2

Gene Symbol	NPFFR2
Entrez Gene	10886
Alt Symbol	GPR74, HLWAR77, NPFF2, NPGPR
Species	Human
Gene Type	protein-coding
Description	neuropeptide FF receptor 2
Other Description	G protein-coupled receptor 74|G-protein coupled receptor 74|G-protein coupled receptor HLWAR77|neuropeptide FF 2|neuropeptide G-protein coupled receptor
Swissprots	Q9NR49 Q96RV1 Q9Y5X5
Accessions	EAX05647 EAX05648 EAX05649 EAX05650 Q9Y5X5 AF119815 AAD22047 AF236083 AAK58513 AF257210 AAF87078 AF268899 AAG41398 AF330053 AAK94197 AJ311393 CAC85427 AK290937 BAF83626 AK308069 BC101636 AAI01637 BC113713 AAI13714 CN285250 XM_011531554 XP_011529856 NM_001144756 NP_001138228 NM_004885 NP_004876 NM_053036 NP_444264
Function	Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Isoform 1 is abundant in placenta. Relatively highly expressed in thymus, testis, and small intestine. Expressed at low levels in several tissues including spleen, prostate, brain, heart, ovary, colon, kidney, lung, liver and pancreas and not expressed in skeletal muscle and leukocytes. Isoform 2 expression is highest in placenta (but at relatively low level compared to isoform 1). Very low level of expression in numerous tissues including adipose tissue and many brain regions. Isoform 3 is expressed in brain and heart and, at lower levels, in kidney, liver, lung and pancreas. {ECO:0000269|PubMed:10079187}.
Top Pathways	Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NPFF2 / NPFFR2 Antibody Blocking Peptide - LS-E2770 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NPFF2 / NPFFR2 Antibody Blocking Peptide - LS-E28718 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NPFF2 / NPFFR2 Antibody Blocking Peptide - LS-E28719 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NPFF2 / NPFFR2 Antibody Blocking Peptide - LS-E28981 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NPFF2 / NPFFR2 Antibody Blocking Peptide - LS-E21796 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NPFF2 / NPFFR2 Antibody Blocking Peptide - LS-E21795 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GPR74/NPFFR2 Protein - H00010886-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

NPFFR2-Antibody-N-term-Blocking-peptide - BP13867a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human NPFFR2 protein - orb245946 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

NPFFR2 Blocking Peptide - 33R-4249 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NPFFR2 Blocking Peptide - 33R-9730 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Neuropeptide FF receptor 2 - H00010886-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

NPFFR2 fusion protein - Ag20249 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NPFFR2 fusion protein - Ag20108 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human NPFFR2, His-tagged - NPFFR2-1341H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant human Neuropeptide FF receptor 2 - CSB-EP015983HU CSB-BP015983HU CSB-MP015983HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant human Neuropeptide FF receptor 2 - CSB-YP015983HU from Cusabio Category Protein Source Yeast Species Human

Neuropeptide FF, Peptide - MBS658862 from MyBioSource Category Peptide Prices $250.00 Sizes 5 mg Source Synthetic peptide

GPR74/NPFFR2 Protein - NBP1-83336PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

NPFFR2 Peptide, Human - M34GP10548H from Creative Peptides Category Peptide Source Synthetic. Species Human

NPFFR2 Recombinant Protein (OPCA02745) - OPCA02745 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human Neuropeptide FF receptor 2 - AP72706 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Human

Neuropeptide FF receptor 2, Recombinant Protein - MBS9422427 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast

Neuropeptide FF receptor 2, Recombinant Protein - MBS969582 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell

Neuropeptide FF receptor 2 (NPFFR2), Recombinant Protein - MBS7023437 from MyBioSource Category Protein Prices $1,320.00, $2,305.00, $3,515.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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