| Gene Symbol |
MYO18A
|
| Entrez Gene |
399687
|
| Alt Symbol |
MYSPDZ, SPR210
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myosin XVIIIA
|
| Other Description |
MAJN|SP-A receptor subunit SP-R210 alphaS|molecule associated with JAK3 N-terminus|myosin 18A|myosin containing PDZ domain|myosin containing a PDZ domain|myosin-XVIIIa|unconventional myosin-XVIIIa
|
| Swissprots |
Q8IXP8 Q5W9G1 Q5H9U3 Q92614 Q5W9F9
|
| Accessions |
EAW51177 EAW51179 EAW51183 Q92614 AB177858 BAD66836 AB177860 BAD66838 AF252258 AAF70181 AK122870 BAG53770 AK294180 BAG57498 AK302505 BAG63783 AK302725 BAG63944 AK303522 BAG64550 AY703984 AAV80770 BC039612 AAH39612 BM544214 CR933614 CAI45931 D86970 BAA13206 NM_078471 NP_510880 NM_203318 NP_976063
|
| Function |
May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. {ECO:0000269|PubMed:18854160, ECO:0000269|PubMed:19837035, ECO:0000269|PubMed:23345592}.
|
| Subcellular Location |
Golgi apparatus. Golgi apparatus, trans- Golgi network. Note=Recruited to the Golgi apparatus by GOLPH3.
|