MYO18A
| Gene Symbol | MYO18A |
|---|---|
| Entrez Gene | 399687 |
| Alt Symbol | MYSPDZ, SPR210 |
| Species | Human |
| Gene Type | protein-coding |
| Description | myosin XVIIIA |
| Other Description | MAJN|SP-A receptor subunit SP-R210 alphaS|molecule associated with JAK3 N-terminus|myosin 18A|myosin containing PDZ domain|myosin containing a PDZ domain|myosin-XVIIIa|unconventional myosin-XVIIIa |
| Swissprots | Q8IXP8 Q5W9G1 Q5H9U3 Q92614 Q5W9F9 |
| Accessions | EAW51177 EAW51179 EAW51183 Q92614 AB177858 BAD66836 AB177860 BAD66838 AF252258 AAF70181 AK122870 BAG53770 AK294180 BAG57498 AK302505 BAG63783 AK302725 BAG63944 AK303522 BAG64550 AY703984 AAV80770 BC039612 AAH39612 BM544214 CR933614 CAI45931 D86970 BAA13206 NM_078471 NP_510880 NM_203318 NP_976063 |
| Function | May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. {ECO:0000269|PubMed:18854160, ECO:0000269|PubMed:19837035, ECO:0000269|PubMed:23345592}. |
| Subcellular Location | Golgi apparatus. Golgi apparatus, trans- Golgi network. Note=Recruited to the Golgi apparatus by GOLPH3. |
Myosin XVIIIa CRISPR/Cas9 KO Plasmid (h) - sc-403216 from Santa Cruz Biotechnology
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Myosin XVIIIa HDR Plasmid (h) - sc-403216-HDR from Santa Cruz Biotechnology
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Myosin XVIIIA Double Nickase Plasmid (h) - sc-403216-NIC from Santa Cruz Biotechnology
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Myosin XVIIIa Double Nickase Plasmid (h2) - sc-403216-NIC-2 from Santa Cruz Biotechnology
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Myosin XVIIIA CRISPR Activation Plasmid (h) - sc-403216-ACT from Santa Cruz Biotechnology
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Myosin XVIIIa CRISPR Activation Plasmid (h2) - sc-403216-ACT-2 from Santa Cruz Biotechnology
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Myosin XVIIIA Lentiviral Activation Particles (h) - sc-403216-LAC from Santa Cruz Biotechnology
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Myosin XVIIIa Lentiviral Activation Particles (h2) - sc-403216-LAC-2 from Santa Cruz Biotechnology
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Myosin XVIIIa siRNA (h) - sc-106272 from Santa Cruz Biotechnology
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Myosin XVIIIa shRNA Plasmid (h) - sc-106272-SH from Santa Cruz Biotechnology
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Myosin XVIIIa shRNA (h) Lentiviral Particles - sc-106272-V from Santa Cruz Biotechnology
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MYO18A RNAi - H00399687-R04 from Novus Biologicals
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MYO18A RNAi - H00399687-R03 from Novus Biologicals
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MISSION® esiRNA - EHU132761 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14849 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14849 from Sigma-Aldrich
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MYO18A siRNA (Human) - CRJ8058 from Cohesion Biosciences
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shRNA set against Human MYO18A (NM_078471.3) - SHH348108 from Creative biogene
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shRNA set against Human MYO18A(NM_078471.3) - SHH212591 from Creative biogene
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shRNA set against Human MYO18A(NM_203318.1) - SHH212609 from Creative biogene
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Human MYO18A siRNA - orb278559 from Biorbyt
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MYO18A shRNA Plasmid (Human) - CHJ8058 from Cohesion Biosciences
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MYO18A miRNA 3'UTR clone - MiUTR1H-06593 from Creative biogene
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MYO18A miRNA 3'UTR clone - MiUTR1H-06594 from Creative biogene
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