Gene Symbol | GANAB |
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Entrez Gene | 23193 |
Alt Symbol | G2AN, GLUII |
Species | Human |
Gene Type | protein-coding |
Description | glucosidase, alpha; neutral AB |
Other Description | HEL-S-164nA|alpha glucosidase II alpha subunit|alpha-glucosidase 2|epididymis secretory sperm binding protein Li 164nA|glucosidase II subunit alpha|neutral alpha-glucosidase AB |
Swissprots | A6NC20 Q9P0X0 Q8WTS9 Q14697 |
Accessions | AAM83349 EAW74045 EAW74046 EAW74047 EAW74048 EAW74049 EAW74050 Q14697 AA618561 AF144074 AAF66685 AJ000332 CAA04006 AK026548 AK026567 AK026997 AK295806 BAG58624 AK299819 BAG61688 AK302752 BAG63965 AK314370 BC005405 AAH05405 BC017433 AAH17433 BC017435 AAH17435 BC034439 BC065266 AAH65266 BG720650 D42041 BAA07642 DC400833 EU794613 ACJ13667 NM_014610 NM_001278192 NP_001265121 NM_001278193 NP_001265122 NM_001278194 NP_001265123 NM_198334 NP_938148 NM_198335 NP_938149 |
Function | Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. {ECO:0000269|PubMed:10929008}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}. Melanosome {ECO:0000269|PubMed:10929008, ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Detected in placenta. {ECO:0000269|PubMed:3881423}. |
Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum |
Human alpha Glucosidase II full length protein - ab132097 from Abcam
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Human alpha Glucosidase II protein fragment - ab91793 from Abcam
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GANAB / Alpha Glucosidase II Antibody Blocking Peptide - LS-E20216 from LifeSpan Bioscience
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Recombinant Human alpha Glucosidase 2 Protein - H00023193-P01 from Novus Biologicals
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alpha Glucosidase 2 Partial Recombinant Protein - H00023193-Q01 from Novus Biologicals
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GANAB Blocking Peptide - 33R-3996 from Fitzgerald
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Alpha-glucosidase 2 / GANAB - H00023193-P01-10 from Acris Antibodies
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Alpha-glucosidase 2 / GANAB - H00023193-P01-25 from Acris Antibodies
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Alpha-glucosidase 2 / GANAB - H00023193-Q01-10 from Acris Antibodies
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Alpha-glucosidase 2 / GANAB - H00023193-Q01-25 from Acris Antibodies
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GANAB fusion protein - Ag9730 from Proteintech Group
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Recombinant Human GANAB, His-tagged - GANAB-27335TH from Creative Biomart
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Recombinant Human GANAB, GST-tagged - GANAB-13150H from Creative Biomart
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Recombinant Human Neutral alpha-glucosidase AB(GANAB) ,partial - CSB-YP617927HU CSB-EP617927HU CSB-BP617927HU CSB-MP617927HU from Cusabio
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Alpha-glucosidase 2 / GANAB (transcript variant 2) - TP318899 from Acris Antibodies
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alpha Glucosidase 2 Recombinant Protein Antigen - NBP1-89806PEP from Novus Biologicals
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alpha Glucosidase 2 Recombinant Protein Antigen - NBP2-49332PEP from Novus Biologicals
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GANAB-Antibody-N-term-Blocking-peptide - BP5653a from Abgent, a WuXi AppTec company
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GANAB Peptide, Human - M34GP06100H from Creative Peptides
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Neutral alpha-glucosidase AB (GANAB), partial, Recombinant Protein - MBS1455000 from MyBioSource
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