| Gene Symbol |
CETP
|
| Entrez Gene |
1071
|
| Alt Symbol |
BPIFF, HDLCQ10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholesteryl ester transfer protein, plasma
|
| Other Description |
BPI fold containing family F|cholesteryl ester transfer protein|lipid transfer protein I
|
| Swissprots |
Q13988 Q13987 Q53YZ1 P11597
|
| Accessions |
AAA51978 AAB86604 AAD14876 AAD14877 AAG21822 AAO12735 AAR03500 AEA76358 EAW82896 EAW82897 P11597 AA999853 AK291586 BAF84275 AK297699 BAG60057 BC025739 AAH25739 BT020064 AAV38867 EU176529 ABW03330 M30185 AAA51977 M83573 AAB59388 XM_006721124 XP_006721187 NM_000078 NP_000069 NM_001286085 NP_001273014
|
| Function |
Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:3600759, PubMed:24293641). Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (PubMed:17237796). {ECO:0000269|PubMed:24293641, ECO:0000303|PubMed:17237796, ECO:0000305|PubMed:3600759}.
|
| Subcellular Location |
Secreted, extracellular space {ECO:0000269|PubMed:24293641}. Note=Secreted in plasma. {ECO:0000250|UniProtKB:P47896}.
|
| Tissue Specificity |
Expressed by the liver and secreted in plasma.
|
![Western Blot: CETP Overexpression Lysate (Adult Normal) [NBL1-09118] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CETP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6916_CETP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09118-img0002.jpg)