Gene Symbol | CETP |
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Entrez Gene | 1071 |
Alt Symbol | BPIFF, HDLCQ10 |
Species | Human |
Gene Type | protein-coding |
Description | cholesteryl ester transfer protein, plasma |
Other Description | BPI fold containing family F|cholesteryl ester transfer protein|lipid transfer protein I |
Swissprots | Q13988 Q13987 Q53YZ1 P11597 |
Accessions | AAA51978 AAB86604 AAD14876 AAD14877 AAG21822 AAO12735 AAR03500 AEA76358 EAW82896 EAW82897 P11597 AA999853 AK291586 BAF84275 AK297699 BAG60057 BC025739 AAH25739 BT020064 AAV38867 EU176529 ABW03330 M30185 AAA51977 M83573 AAB59388 XM_006721124 XP_006721187 NM_000078 NP_000069 NM_001286085 NP_001273014 |
Function | Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:3600759, PubMed:24293641). Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (PubMed:17237796). {ECO:0000269|PubMed:24293641, ECO:0000303|PubMed:17237796, ECO:0000305|PubMed:3600759}. |
Subcellular Location | Secreted, extracellular space {ECO:0000269|PubMed:24293641}. Note=Secreted in plasma. {ECO:0000250|UniProtKB:P47896}. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
CETP CRISPR/Cas9 KO Plasmid (h) - sc-405829 from Santa Cruz Biotechnology
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CETP HDR Plasmid (h) - sc-405829-HDR from Santa Cruz Biotechnology
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CETP Double Nickase Plasmid (h) - sc-405829-NIC from Santa Cruz Biotechnology
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CETP Double Nickase Plasmid (h2) - sc-405829-NIC-2 from Santa Cruz Biotechnology
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CETP CRISPR Activation Plasmid (h) - sc-405829-ACT from Santa Cruz Biotechnology
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CETP CRISPR Activation Plasmid (h2) - sc-405829-ACT-2 from Santa Cruz Biotechnology
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CETP Lentiviral Activation Particles (h) - sc-405829-LAC from Santa Cruz Biotechnology
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CETP Lentiviral Activation Particles (h2) - sc-405829-LAC-2 from Santa Cruz Biotechnology
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CETP siRNA (h) - sc-45913 from Santa Cruz Biotechnology
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CETP shRNA Plasmid (h) - sc-45913-SH from Santa Cruz Biotechnology
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CETP shRNA (h) Lentiviral Particles - sc-45913-V from Santa Cruz Biotechnology
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CETP RNAi - H00001071-R01 from Novus Biologicals
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MISSION® esiRNA - EHU023931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1080 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1080 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01334 from Sigma-Aldrich
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CETP siRNA (Human) - CRH0772 from Cohesion Biosciences
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CETP - MBS8221285 from MyBioSource
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shRNA set against Human CETP (NM_000078.2) - SHH262361 from Creative biogene
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Human CETP siRNA - orb261274 from Biorbyt
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CETP shRNA Plasmid (Human) - CHH0772 from Cohesion Biosciences
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CETP miRNA 3'UTR clone - MiUTR3H-00417 from Creative biogene
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