ITLN1

Gene Symbol ITLN1
Entrez Gene 55600
Alt Symbol HL-1, HL1, INTL, ITLN, LFR, hIntL, omentin
Species Human
Gene Type protein-coding
Description intelectin 1 (galactofuranose binding)
Other Description ITLN-1|endothelial lectin HL-1|galactofuranose-binding lectin|intelectin-1|intestinal lactoferrin receptor
Swissprots Q8WWA0 Q9NP67 Q6YDJ3 Q5VYI4 Q5IWS4
Accessions EAW52688 EAW52689 EAW52690 Q8WWA0 AB036706 BAA96094 AF271386 AAM20741 AK000029 BAA90893 AK222533 BAD96253 AY065972 AAL58073 AY157361 AAO17800 AY157362 AAO17801 AY358359 AAQ88725 AY549722 AAS49907 AY619691 AAU88047 AY619692 AAU88048 BC020664 AAH20664 CR457224 CAG33505 EU832610 ACE87701 EU832681 ACE87013 HQ447701 ADQ32186 NM_017625 NP_060095
Function Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism. {ECO:0000269|PubMed:11313366, ECO:0000269|PubMed:16531507}.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Enriched in lipid rafts. {ECO:0000250}.
Tissue Specificity Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus. {ECO:0000269|PubMed:11181563, ECO:0000269|PubMed:11313366, ECO:0000269|PubMed:11747454, ECO:0000269|PubMed:16531507}.

Intelectin-1/2 (3G1B3) - sc-130923 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Intelectin-1/2 (S-14) - sc-104334 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Intelectin-1 (N-12) - sc-104332 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ITLN1 antibody - ab198025 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ITLN1 antibody (ab198025) at 1/400 dilution + Human fetal intestine tissue lysate at 40 µg

Anti-ITLN1 antibody - ab118232 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab112328 at 1/100 dilution staining ITLN1 in Formalin-fixed, Paraffin-embedded Human fetal small intestine tissue by Immunohistochemistry.

Anti-ITLN1 antibody - ab102780 from Abcam

Prices $359.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ITLN1 antibody (ab102780) at 1/100 dilution + MCF-7 cell line lysates at 35 µg

Anti-ITLN1 antibody - ab166983 from Abcam

Host Sheep
Clonality Polyclonal

Anti-ITLN1 antibody [17] - ab101101 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 17
Anti-ITLN1 antibody [17] (ab101101) at 1/1000 dilution + HEK293 whole cell lysate

Anti-ITLN1 antibody [AT6C11] - ab180259 from Abcam

Prices $357.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT6C11
Lane 1 :  Anti-ITLN1 antibody [AT6C11] (ab180259) at 1/250 dilutionLane 2 :  Anti-ITLN1 antibody [AT6C11] (ab180259) at 1/500 dilutionLane 1 : 293T lysateLane 2 : 293T lysateLysates/proteins at 60 µg per lane.Secondarygoat anti-mouse secondary antibody conjugated to HRPdeveloped using the ECL technique

Anti-ITLN1 antibody [Saly-2] - ab195384 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Saly-2

Anti-ITLN1 / Omentin Antibody - LS-C343032 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ITLN1 / Omentin Antibody (Biotin) - LS-C343034 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ITLN1 / Omentin Antibody (N-Terminus) - LS-C343374 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ITLN1 / Omentin Antibody (N-Terminus, Biotin) - LS-C343279 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ITLN1 / Omentin Antibody - LS-C343544 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ITLN1 / Omentin Antibody (aa28-270) - LS-C294698 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ITLN1 / Omentin.

Anti-ITLN1 / Omentin Antibody (aa31-253) - LS-C294702 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ITLN1 / Omentin.

Anti-ITLN1 / Omentin Antibody (Biotin) - LS-C343572 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ITLN1 / Omentin Antibody (aa101-292) - LS-C294699 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ITLN1 / Omentin.

Anti-ITLN1 / Omentin Antibody - LS-C343704 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ITLN1 / Omentin Antibody (clone Saly-1) - LS-C343731 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Saly-1

Anti-ITLN1 / Omentin Antibody (clone Lecty-1) - LS-C344934 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Lecty-1

Anti-ITLN1 / Omentin Antibody (clone AT6C11) - LS-C200865 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT6C11
Western Blot: The lysate of 293T (60 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human ITLN1 antibody(1:250-1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Anti-ITLN1 / Omentin Antibody (aa27-168) IHC-plus™ - LS-B10492 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-ITLN1 / Omentin Antibody - LS-C346303 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using ITLN1 antibody. Blue: DAPI for nuclear staining.
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