DCD

Gene Symbol DCD
Entrez Gene 117159
Alt Symbol AIDD, DCD-1, DSEP, HCAP, PIF
Species Human
Gene Type protein-coding
Description dermcidin
Other Description diffusible survival/evasion peptide|preproteolysin|proteolysis inducing factor|survival promoting peptide
Swissprots A5JHP3 P58461 A5JHP2 P81605 Q53YJ2
Accessions AAK94785 AAL25801 EAW96794 P81605 AF144011 AAL18349 AY590150 AAS99907 BC062682 AAH62682 BC069108 AAH69108 BP313072 EF503687 ABQ53649 EF503688 ABQ53650 EF503689 ABQ53651 HQ447604 ADQ32090 NM_001300854 NP_001287783 NM_053283 NP_444513
Function DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.
Subcellular Location Secreted.
Tissue Specificity Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml.

Dermcidin (E-7) - sc-393728 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dermcidin (E-7): sc-393728. Western blot analysis of Dermcidin expression in non-transfected (A) and human Dermcidin transfected (B) CMV whole cell lysates.

Dermcidin (G-81) - sc-33656 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dermcidin (G-81): sc-33656. Western blot analysis of human recombinant Dermcidin fusion protein.

Dermcidin (H-12) - sc-398429 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dermcidin (H-12): sc-398429. Western blot analysis of Dermcidin expression in non-transfected (A) and human Dermcidin transfected (B) CMV whole cell lysates.

Dermcidin (A-20) - sc-27467 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dermcidin (A-20): sc-27467. Western blot analysis of human recombinant Dermcidin fusion protein.

Dermcidin (S-19) - sc-27466 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dermcidin (S-19): sc-27466. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing membrane and cytoplasmic staining of keratinocytes and Langerhans cells and cytoplasmic staining of melanocytes.

Dermcidin (N-20) - sc-27465 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dermcidin (N-20): sc-27465. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing membrane and cytoplasmic staining of keratinocytes and Langerhans cells and cytoplasmic staining of fibroblasts.

Dermcidin (H-91) - sc-32926 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Dermcidin antibody - ab52138 from Abcam

Prices $378.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab52138 (1/300) detecting Dermcidin in frozen skeletal muscle tissue sections (mouse). Tissues were fixed with paraformaldehyde and blocked in 5% BSA. For further experimental details please refer to abreview.See Abreview

Anti-Dermcidin antibody - ab52133 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-Dermcidin antibody - C-terminal - ab175519 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Dermcidin antibody - C-terminal (ab175519) at 1/1000 dilution + T47D cell line lysate at 35 µgdeveloped using the ECL technique

Anti-DCD / Dermcidin Antibody (aa60-88) - LS-C128573 from LifeSpan Bioscience

Prices $405.00
Sizes 20 µl
Host Rabbit
Clonality Polyclonal

Anti-DCD / Dermcidin Antibody (aa96-110) - LS-C128574 from LifeSpan Bioscience

Prices $405.00
Sizes 20 µl
Host Rabbit
Clonality Polyclonal

Anti-DCD / Dermcidin Antibody (clone GF1) - LS-C189920 from LifeSpan Bioscience

Prices $560.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone GF1

Anti-DCD / Dermcidin Antibody - LS-C285486 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DCD / Dermcidin Antibody (aa18-110, Biotin) - LS-C300432 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DCD / Dermcidin Antibody (clone G-81) IHC-plus™ - LS-B6540 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone G-81
Anti-DCD / Dermcidin antibody IHC of human skin, eccrine sweat gland. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6540 concentration 10 ug/ml.

Anti-DCD / Dermcidin Antibody (aa18-110, FITC) - LS-C303316 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DCD / Dermcidin Antibody (FITC) - LS-C317131 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DCD / Dermcidin Antibody (Biotin) - LS-C317135 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DCD / Dermcidin Antibody (aa18-110) - LS-C293674 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant DCD / Dermcidin.

Anti-DCD / Dermcidin Antibody (HRP) - LS-C317136 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DCD / Dermcidin Antibody (aa74-103) - LS-C167290 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DCD Antibody (RB18706) IHC of formalin-fixed and paraffin-embedded human skin tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-DCD / Dermcidin Antibody - LS-C346322 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of MCF7 cell using DCD antibody. Blue: DAPI for nuclear staining.

Dermcidin Antibody (G-81) - NBP1-49620 from Novus Biologicals

Prices $429.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone G-81

Dermcidin/DCD Polyclonal Antibody - bs-12996R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
293T cell lysates probed with Anti-Dermcidin/DCD Polyclonal Antibody, Unconjugated (bs-12996R) at 1:300 overnight at 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:5000 for 90 min at 37˚C.\\n
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