RAD23B

Gene Symbol RAD23B
Entrez Gene 5887
Alt Symbol HHR23B, HR23B, P58
Species Human
Gene Type protein-coding
Description RAD23 homolog B (S. cerevisiae)
Other Description RAD23, yeast homolog of, B|UV excision repair protein RAD23 homolog B|XP-C repair complementing complex 58 kDa|XP-C repair complementing protein|XP-C repair-complementing complex 58 kDa protein
Swissprots Q7Z5K8 B3KWK8 G5E9P0 P54727 Q8WUB0
Accessions AAN47194 EAW59016 EAW59017 P54727 AI285544 AI375313 AK125226 BAG54170 AK223479 BAD97199 AK293532 BAG57014 AK297986 BAH12700 AK316189 BAH14560 AL540969 AU125295 AW402384 AY313777 AAP81008 BC015805 BC020973 AAH20973 BE894394 BG678535 BI460482 BQ230600 BQ277025 BQ774932 CA866470 D21090 BAA04652 DC404422 DQ890563 ABM92180 DQ893726 ABM84652 NM_001244713 NP_001231642 NM_001244724 NP_001231653 NM_002874 NP_002865
Function The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn rec
Subcellular Location Nucleus. Cytoplasm. Note=The intracellular distribution is cell cycle dependent. Localized to the nucleus and the cytoplasm during G1 phase. Nuclear levels decrease during S- phase; upon entering mitosis, relocalizes in the cytoplasm without association with chromatin.
Top Pathways Nucleotide excision repair, Protein processing in endoplasmic reticulum

Rad23B (D4W7F) Rabbit mAb - 13525 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4W7F
Western blot analysis of extracts from various cell lines using Rad23B (D4W7F) Rabbit mAb.

Rad23B (C-4) - sc-166507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rad23B (C-4): sc-166507. Western blot analysis of Rad23B expression in non-transfected: sc-117752 (A) and mouse Rad23B transfected: sc-125881 (B) 293T whole cell lysates.

Rad23B (E-10) - sc-377409 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rad23B (E-10): sc-377409. Western blot analysis of Rad23B expression in K-562 (A) and HeLa (B) whole cell lysates.

Rad23B (H-120) - sc-67225 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rad23B (H-120): sc-67225. Western blot analysis of Rad23B expression in HeLa whole cell lysate.

Rad23B (H-8) - sc-137088 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rad23B (H-8): sc-137088. Western blot analysis of Rad23B expression in non-transfected 293T: sc-117752 (A), mouse Rad23B transfected 293T: sc-125881 (B) and K-562 (C) whole cell lysates.

Rad23B (M-120) - sc-67226 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rad23B (M-120): sc-67226. Western blot analysis of Rad23B expression in HeLa whole cell lysate.

Rad23B (N-12) - sc-49041 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rad23B (N-12): sc-49041. Immunoperoxidase staining of formalin fixed, paraffin-embedded human esophagus tissue showing nuclear and cytoplasmic staining of squamous epithelial cells.

Rad23B (F-8) - sc-390019 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rad23B (F-8): sc-390019. Western blot analysis of Rad23B expression in K-562 (A) and HeLa (B) whole cell lysates.

Rad23B (P-18) - sc-49042 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rad23B (P-18): sc-49042. Western blot analysis of Rad23B expression in HeLa whole cell lysate.

Rad23B (16) - sc-136052 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
Rad23B (16): sc-136052. Western blot analysis of Rad23B expression in A-431 whole cell lysate.

Anti-hHR23b antibody - ab3835 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-hHR23b antibody (ab3835) at 1/500 dilution + HeLa whole cell lysate at 33 µgSecondaryIRDye 800 conjugated Rabbit anti-Goat IgG [H&L] at 1/10000 dilution

Anti-hHR23b antibody - ab88503 from Abcam

Prices $379.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-hHR23b antibody (ab88503) at 1/500 dilution + Human liver lysate at 50 µg

Anti-hHR23b antibody - ab123790 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-hHR23b antibody (ab123790) at 1/100 dilution + A549 cell line lysate at 35 µg

Anti-hHR23b antibody - ab138290 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-hHR23b antibody (ab138290) at 1/500 dilution + Jurkat cell lysate at 30 µg

Anti-hHR23b antibody [2857D7a] - ab70602 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2857D7a
Anti-hHR23b antibody [2857D7a] (ab70602) at 0.2 µg/ml + Whole cell lysate from HeLa cells at 25 µg

Anti-RAD23B / HR23B Antibody - LS-C75316 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-RAD23B / HR23B Antibody (C-Terminus) - LS-C145076 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RAD23B / HR23B Antibody (clone 2857D7a) - LS-C184660 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2857D7a

Anti-RAD23B / HR23B Antibody (Lys27) - LS-C192028 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAD23B / HR23B Antibody (aa10-40, AP) - LS-C267746 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAD23B / HR23B Antibody (aa10-40, APC) - LS-C267748 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAD23B / HR23B Antibody (aa10-40, Biotin) - LS-C267747 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAD23B / HR23B Antibody (aa10-40, Azide-free, HRP) - LS-C267749 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAD23B / HR23B Antibody (aa10-40, PE) - LS-C267751 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RAD23B / HR23B Antibody (aa10-40, FITC) - LS-C267750 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more