RAD23B

Gene Symbol	RAD23B
Entrez Gene	5887
Alt Symbol	HHR23B, HR23B, P58
Species	Human
Gene Type	protein-coding
Description	RAD23 homolog B (S. cerevisiae)
Other Description	RAD23, yeast homolog of, B|UV excision repair protein RAD23 homolog B|XP-C repair complementing complex 58 kDa|XP-C repair complementing protein|XP-C repair-complementing complex 58 kDa protein
Swissprots	Q7Z5K8 B3KWK8 G5E9P0 P54727 Q8WUB0
Accessions	AAN47194 EAW59016 EAW59017 P54727 AI285544 AI375313 AK125226 BAG54170 AK223479 BAD97199 AK293532 BAG57014 AK297986 BAH12700 AK316189 BAH14560 AL540969 AU125295 AW402384 AY313777 AAP81008 BC015805 BC020973 AAH20973 BE894394 BG678535 BI460482 BQ230600 BQ277025 BQ774932 CA866470 D21090 BAA04652 DC404422 DQ890563 ABM92180 DQ893726 ABM84652 NM_001244713 NP_001231642 NM_001244724 NP_001231653 NM_002874 NP_002865
Function	The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn rec
Subcellular Location	Nucleus. Cytoplasm. Note=The intracellular distribution is cell cycle dependent. Localized to the nucleus and the cytoplasm during G1 phase. Nuclear levels decrease during S- phase; upon entering mitosis, relocalizes in the cytoplasm without association with chromatin.
Top Pathways	Nucleotide excision repair, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human hHR23b full length protein - ab114492 from Abcam Category Protein Source Wheat germ Species Human

Human hHR23b protein fragment - ab114493 from Abcam Category Protein Source Wheat germ Species Human

RAD23B / HR23B Antibody Blocking Peptide - LS-E3662 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD23B / HR23B Antibody Blocking Peptide - LS-E20523 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAD23B / HR23B Antibody Blocking Peptide - LS-E20524 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human hHR23b Protein - H00005887-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

hHR23b Partial Recombinant Protein - H00005887-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

hHR23b Peptide - NBP1-96767 from Novus Biologicals Category Peptide Prices $169.00 Sizes 50 µg

RAD23B-Antibody-N-term-Blocking-Peptide - BP14862a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RAD23B Blocking Peptide - 33R-7736 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RAD23B Blocking Peptide - 33R-7658 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RAD23B Blocking Peptide - abx063176 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Monkey

RAD23B - H00005887-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RAD23B - H00005887-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RAD23B - H00005887-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RAD23B - H00005887-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RAD23B control peptide - AP09213CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

RAD23B fusion protein - Ag2763 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RAD23B - RAD23B-27732TH from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human RAD23B - RAD23B-29311TH from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human RAD23B, GST-tagged - RAD23B-2154H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant RAD23 Homolog B (RAD23B) - RPP751Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

HR23B Peptide - 000-001-391 from Rockland Immunochemicals Inc Category Peptide Prices $98.00 Sizes 50 µg Species Human

RAD23B Blocking Peptide - CBP1982 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Monkey

Rad23B (K27) Peptide - BS2424P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

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