NPRL3

Gene Symbol	NPRL3
Entrez Gene	8131
Alt Symbol	C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11
Species	Human
Gene Type	protein-coding
Description	nitrogen permease regulator-like 3 (S. cerevisiae)
Other Description	-14 gene protein|alpha-globin regulatory element-containing gene protein|conserved gene telomeric to alpha globin cluster|nitrogen permease regulator 3-like protein
Swissprots	Q1W6H0 Q12980 Q92469 Q4TT56 D3DU40
Accessions	ABD95907 CAB06556 CAI94885 CAI94886 CAI95611 CAI95612 CAM13055 EAW85865 EAW85867 EAW85868 Q12980 AK026990 AK090717 BAG52219 AK125420 AK294228 BAH11706 AK298795 BAH12872 AK300736 BAH13336 BC004185 AAH04185 BC012825 AAH12825 BC020392 DA075508 DA258664 DA658076 DC384076 HQ448276 ADQ32756 X90857 CAA62368 XM_011522668 XP_011520970 XM_011522669 XP_011520971 XM_011522670 XP_011520972 XM_011522671 XP_011520973 XM_011522672 XP_011520974 XM_011522673 XP_011520975 XM_011522674 XP_011520976 XM_011522675 XP_011520977 XM_011522676 XP_011520978 XM_011522677 XP_011520979 XM_011522678 XP_011520980 XM_011522679 XP_011520981 XM_011522680 XP_011520982 XM_011522681 XP_011520983 NM_001039476 NP_001034565 NM_001077350 NP_001070818 NM_001243247 NP_001230176 NM_001243248 NP_001230177 NM_001243249 NP_001230178 NM_012075
Function	As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. {ECO:0000269|PubMed:23723238}.
Tissue Specificity	Widely expressed.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NPRL3 protein fragment - ab159949 from Abcam Category Protein Source Wheat germ Species Human

NPRL3 Antibody Blocking Peptide - LS-E27788 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NPRL3 Partial Recombinant Protein - H00008131-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

NPRL3 Peptide - AC21-2600-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MARE - H00008131-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MARE - H00008131-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

C16orf35 fusion protein - Ag24045 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET30a Species Human

Recombinant Human NPRL3 - NPRL3-497H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Nitrogen permease regulator 3-like protein(NPRL3) - CSB-YP619643HU CSB-EP619643HU CSB-BP619643HU CSB-MP619643HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NPRL3 Recombinant Protein Antigen - NBP1-88447PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NPRL3-Blocking-Peptide-N-Term - BP21877a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NPRL3 Peptide, Human - M34GP10569H from Creative Peptides Category Peptide Source Synthetic. Species Human

Nprl3 Immunizing peptide - orb66281 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

Nitrogen permease regulator 3-like protein (NPRL3), Recombinant Protein - MBS1378162 from MyBioSource Category Protein Prices $1,365.00, $1,365.00, $1,585.00, $1,585.00, $2,270.00, $2,270.00, $2,735.00, $2,735.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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