Gene Symbol | RTN4R |
---|---|
Entrez Gene | 65078 |
Alt Symbol | NGR, NOGOR |
Species | Human |
Gene Type | protein-coding |
Description | reticulon 4 receptor |
Other Description | Nogo-66 receptor|UNQ330/PRO526|nogo receptor|reticulon-4 receptor |
Swissprots | Q9BZR6 D3DX28 |
Accessions | CBL54388 EAX02975 EAX02976 Q9BZR6 AF283463 AAG53612 AK054602 AL834449 CAD39109 AM393268 CAL38146 BC011787 AAH11787 BM762412 CR456360 CAG30246 CU013070 CAK54501 CU013358 CAK54800 DQ892891 ABM83817 DQ896138 ABM87137 NM_023004 NP_075380 |
Function | Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
Tissue Specificity | Widespread in the brain but highest levels in the gray matter. Low levels in heart and kidney not expressed in oligodendrocytes (white matter). |