Gene Symbol | RTN4R |
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Entrez Gene | 65078 |
Alt Symbol | NGR, NOGOR |
Species | Human |
Gene Type | protein-coding |
Description | reticulon 4 receptor |
Other Description | Nogo-66 receptor|UNQ330/PRO526|nogo receptor|reticulon-4 receptor |
Swissprots | Q9BZR6 D3DX28 |
Accessions | CBL54388 EAX02975 EAX02976 Q9BZR6 AF283463 AAG53612 AK054602 AL834449 CAD39109 AM393268 CAL38146 BC011787 AAH11787 BM762412 CR456360 CAG30246 CU013070 CAK54501 CU013358 CAK54800 DQ892891 ABM83817 DQ896138 ABM87137 NM_023004 NP_075380 |
Function | Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
Tissue Specificity | Widespread in the brain but highest levels in the gray matter. Low levels in heart and kidney not expressed in oligodendrocytes (white matter). |
Nogo-R CRISPR/Cas9 KO Plasmid (h) - sc-403012 from Santa Cruz Biotechnology
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Nogo-R HDR Plasmid (h) - sc-403012-HDR from Santa Cruz Biotechnology
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Nogo-R Double Nickase Plasmid (h) - sc-403012-NIC from Santa Cruz Biotechnology
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Nogo-R Double Nickase Plasmid (h2) - sc-403012-NIC-2 from Santa Cruz Biotechnology
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Nogo-R CRISPR Activation Plasmid (h) - sc-403012-ACT from Santa Cruz Biotechnology
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Nogo-R CRISPR Activation Plasmid (h2) - sc-403012-ACT-2 from Santa Cruz Biotechnology
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Nogo-R Lentiviral Activation Particles (h) - sc-403012-LAC from Santa Cruz Biotechnology
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Nogo-R Lentiviral Activation Particles (h2) - sc-403012-LAC-2 from Santa Cruz Biotechnology
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Nogo-R siRNA (h) - sc-42140 from Santa Cruz Biotechnology
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Nogo-R shRNA Plasmid (h) - sc-42140-SH from Santa Cruz Biotechnology
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Nogo-R shRNA (h) Lentiviral Particles - sc-42140-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU122281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18739 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18739 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01717 from Sigma-Aldrich
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RTN4R siRNA (Human) - CRJ2174 from Cohesion Biosciences
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RTN4R - MBS8236727 from MyBioSource
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shRNA set against Human RTN4R (NM_023004.5) - SHH400568 from Creative biogene
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shRNA set against Human RTN4R(NM_023004.5) - SHR201228 from Creative biogene
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Human RTN4R siRNA - orb272675 from Biorbyt
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RTN4R shRNA Plasmid (Human) - CHJ2174 from Cohesion Biosciences
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RTN4R miRNA 3'UTR clone - MiUTR1H-09071 from Creative biogene
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