Gene Symbol | FCER1A |
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Entrez Gene | 2205 |
Alt Symbol | FCE1A, FcERI |
Species | Human |
Gene Type | protein-coding |
Description | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
Other Description | Fc IgE receptor, alpha polypeptide|Fc epsilon RI alpha-chain|Fc-epsilon RI-alpha|high affinity immunoglobulin epsilon receptor alpha-subunit|high affinity immunoglobulin epsilon receptor subunit alpha|igE Fc receptor subunit alpha|immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide |
Swissprots | P12319 |
Accessions | AAA16115 BAB84120 CAA01564 CAA82702 CAN36268 EAW52789 P12319 BC005912 AAH05912 BC015185 BC015195 AAH15195 DQ893131 ABM84057 DQ896411 ABM87410 DQ896467 ABM87466 J03605 AAA36204 X06948 CAA30025 NM_002001 NP_001992 |
Function | Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Top Pathways | Fc epsilon RI signaling pathway, Asthma, Sphingolipid signaling pathway |
Fc ε RIα (C-16) - sc-33482 from Santa Cruz Biotechnology
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Fc ε RIα (H-90) - sc-68942 from Santa Cruz Biotechnology
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Fc ε RIα (Q-17) - sc-33480 from Santa Cruz Biotechnology
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Fc ε RIα (X-22) - sc-100279 from Santa Cruz Biotechnology
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Anti-Fc epsilon RI antibody - ab31494 from Abcam
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Anti-Fc epsilon RI antibody - ab54660 from Abcam
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Anti-Fc epsilon RI antibody [1F2A9] - ab166812 from Abcam
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Anti-Fc epsilon RI antibody [9E1] - ab54411 from Abcam
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Anti-Fc epsilon RI antibody [AER-37 (CRA1)], prediluted (Allophycocyanin) - ab155369 from Abcam
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Anti-Fc epsilon RI antibody [AER-37 (CRA1)] - Low endotoxin, Azide free - ab171278 from Abcam
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Anti-Fc epsilon RI antibody [CRA1] (Biotin) - ab122882 from Abcam
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Anti-Fc epsilon RI antibody [CRA2] (Biotin) - ab122915 from Abcam
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Anti-Fc epsilon RI antibody [CRA2] (FITC) - ab122891 from Abcam
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Anti-FcERI / Fc Epsilon RI Antibody - LS-C192774 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody - LS-C335175 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody (aa42-103, clone 1F2A9) - LS-C191799 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody (aa42-103, clone 1F2A9) - LS-C191798 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody (clone AER-37 (CRA1), FITC) - LS-C105808 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody (aa144-193) - LS-C111011 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody (clone AER-37 (CRA1), Biotin) - LS-C106472 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody - LS-C310345 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody (aa35-84) - LS-C116291 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody - LS-C23514 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody - LS-C23513 from LifeSpan Bioscience
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Anti-FcERI / Fc Epsilon RI Antibody (PE) - LS-C128975 from LifeSpan Bioscience
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