Gene Symbol | FCER1A |
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Entrez Gene | 2205 |
Alt Symbol | FCE1A, FcERI |
Species | Human |
Gene Type | protein-coding |
Description | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
Other Description | Fc IgE receptor, alpha polypeptide|Fc epsilon RI alpha-chain|Fc-epsilon RI-alpha|high affinity immunoglobulin epsilon receptor alpha-subunit|high affinity immunoglobulin epsilon receptor subunit alpha|igE Fc receptor subunit alpha|immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide |
Swissprots | P12319 |
Accessions | AAA16115 BAB84120 CAA01564 CAA82702 CAN36268 EAW52789 P12319 BC005912 AAH05912 BC015185 BC015195 AAH15195 DQ893131 ABM84057 DQ896411 ABM87410 DQ896467 ABM87466 J03605 AAA36204 X06948 CAA30025 NM_002001 NP_001992 |
Function | Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Top Pathways | Fc epsilon RI signaling pathway, Asthma, Sphingolipid signaling pathway |
Active human Fc epsilon RI protein fragment - ab182693 from Abcam
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Human Fc epsilon RI full length protein - ab114334 from Abcam
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Human Fc epsilon RI protein fragment - ab171505 from Abcam
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Fc epsilon RI Recombinant Protein - H00002205-P01 from Novus Biologicals
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Recombinant Human Fc epsilon RI Protein - NBP2-23043 from Novus Biologicals
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Recombinant Human Fc epsilon RI alpha, CF - 6678-FC-050 from R&D Systems
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Human FCER1A protein (His Tag) - orb138850 from Biorbyt
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FCER1A Blocking Peptide - 33R-4229 from Fitzgerald
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FCER1A Blocking Peptide - 33R-6827 from Fitzgerald
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FCER1A protein (His tag) - 80R-3527 from Fitzgerald
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FCER1A (26-205, His-tag) - AR51215PU-N from Acris Antibodies
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FCER1A (26-205, His-tag) - AR51215PU-S from Acris Antibodies
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FCER1A - H00002205-P01-10 from Acris Antibodies
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FCER1A - H00002205-P01-25 from Acris Antibodies
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FCER1A, 26-205aa, Human, His tag, E.coli - 01-P2394 from ARP American Research Products
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FCER1A Recombinant Protein - 96-304 from ProSci
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FCER1A fusion protein - ag1398 from Proteintech Group
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Recombinant Human FCER1A - BP001519-CA53 from Syd Labs
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Recombinant Human FCER1A, GST-tagged - FCER1A-28166TH from Creative Biomart
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Recombinant Human FCER1A, His tagged - FCER1A-8563H from Creative Biomart
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Recombinant Human Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, His-tagged - FCER1A-311H from Creative Biomart
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Recombinant Human FCER1A, His-tagged - FCER1A-204H from Creative Biomart
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Recombinant Human FCER1A, His-tagged, Biotinylated - FCER1A-193H from Creative Biomart
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Recombinant Human FCER1A - FCER1A-237H from Creative Biomart
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Recombinant Human FCER1A, His-tagged - FCER1A-725H from Creative Biomart
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