Gene Symbol | MC5R |
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Entrez Gene | 4161 |
Alt Symbol | MC2 |
Species | Human |
Gene Type | protein-coding |
Description | melanocortin 5 receptor |
Other Description | melanocortin receptor 5|melanocortin-5 receptor |
Swissprots | Q502V1 B0YJ34 P33032 |
Accessions | AAA59566 AAB60376 AAP23196 ACA06012 CAA80962 EAX01504 P33032 BC069153 AAH69153 BC069545 AAH69545 BC095531 AAH95531 NM_005913 NP_005904 |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in the brain but not in the melanoma cells. |
Top Pathways | Neuroactive ligand-receptor interaction |
MC5-R (C-18) - sc-7644 from Santa Cruz Biotechnology
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MC5-R (H-55) - sc-28993 from Santa Cruz Biotechnology
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Anti-MC5 Receptor antibody - ab87470 from Abcam
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Anti-MC5 Receptor antibody - ab188960 from Abcam
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Anti-MC5 Receptor antibody - ab92287 from Abcam
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Anti-MC5 Receptor antibody - ab96049 from Abcam
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Anti-MC5 Receptor antibody - ab137290 from Abcam
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Anti-MC5 Receptor antibody [EPR8386] - ab133656 from Abcam
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Anti-MC5 Receptor antibody - C-terminal - ab139151 from Abcam
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Anti-MC5 Receptor antibody - N-terminal - ab140852 from Abcam
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Anti-MC5R / MC5 Receptor Antibody (N-Terminus) - LS-C8987 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa280-308, APC) - LS-C262797 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa280-308, AP) - LS-C262798 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa1-45) - LS-C185949 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (Glu308) - LS-C177204 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa280-308, FITC) - LS-C262799 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa271-320) - LS-C120739 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa280-308) - LS-C158109 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa280-308, PE) - LS-C262801 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa280-308, Azide-free, HRP) - LS-C262802 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa280-308, Biotin) - LS-C262805 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa259-308) - LS-C292173 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (aa280-308) - LS-C329821 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody - LS-C341243 from LifeSpan Bioscience
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Anti-MC5R / MC5 Receptor Antibody (Extracellular Domain, clone EPR8386) IHC-plus™ - LS-B9635 from LifeSpan Bioscience
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