| Gene Symbol |
MC5R
|
| Entrez Gene |
4161
|
| Alt Symbol |
MC2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
melanocortin 5 receptor
|
| Other Description |
melanocortin receptor 5|melanocortin-5 receptor
|
| Swissprots |
Q502V1 B0YJ34 P33032
|
| Accessions |
AAA59566 AAB60376 AAP23196 ACA06012 CAA80962 EAX01504 P33032 BC069153 AAH69153 BC069545 AAH69545 BC095531 AAH95531 NM_005913 NP_005904
|
| Function |
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in the brain but not in the melanoma cells.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|