Gene Symbol |
CALR3
|
Entrez Gene |
125972
|
Alt Symbol |
CMH19, CRT2, CT93
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
calreticulin 3
|
Other Description |
calreticulin-2|calreticulin-3|calsperin|cancer/testis antigen 93
|
Swissprots |
Q96LN3 Q96L12 D9N574
|
Accessions |
CAK18762 EAW84546 Q96L12 AA724299 AA910019 AB576176 BAJ14705 AK058084 BAB71655 BC014595 AAH14595 BP370084 DB459545 DB510196 DQ890903 ABM81829 DQ894056 ABM84982 NM_145046 NP_659483
|
Function |
During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility (By similarity). CALR3 capacity for calcium- binding may be absent or much lower than that of CALR. {ECO:0000250, ECO:0000269|PubMed:21590275}.
|
Subcellular Location |
Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:21590275}.
|
Tissue Specificity |
Testis specific. {ECO:0000269|PubMed:12384296}.
|