Gene Symbol | CALR3 |
---|---|
Entrez Gene | 125972 |
Alt Symbol | CMH19, CRT2, CT93 |
Species | Human |
Gene Type | protein-coding |
Description | calreticulin 3 |
Other Description | calreticulin-2|calreticulin-3|calsperin|cancer/testis antigen 93 |
Swissprots | Q96LN3 Q96L12 D9N574 |
Accessions | CAK18762 EAW84546 Q96L12 AA724299 AA910019 AB576176 BAJ14705 AK058084 BAB71655 BC014595 AAH14595 BP370084 DB459545 DB510196 DQ890903 ABM81829 DQ894056 ABM84982 NM_145046 NP_659483 |
Function | During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility (By similarity). CALR3 capacity for calcium- binding may be absent or much lower than that of CALR. {ECO:0000250, ECO:0000269|PubMed:21590275}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:21590275}. |
Tissue Specificity | Testis specific. {ECO:0000269|PubMed:12384296}. |