DAD1

Gene Symbol DAD1
Entrez Gene 1603
Alt Symbol OST2
Species Human
Gene Type protein-coding
Description defender against cell death 1
Other Description DAD-1|dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1|oligosaccharyl transferase subunit DAD1|oligosaccharyltransferase 2 homolog|oligosaccharyltransferase subunit 2 (non-catalytic)
Swissprots P61803 D3DS25 Q6FGA3
Accessions AAB58540 AAO74827 EAW66252 EAW66253 P61803 AK223129 BAD96849 BC007403 AAH07403 BC009798 AAH09798 BC038575 BP198316 CR407682 CAG28610 CR542204 CAG47001 D15057 BAA03650 DQ892868 ABM83794 DQ896117 ABM87116 NM_001344 NP_001335
Function Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways N-Glycan biosynthesis, Protein processing in endoplasmic reticulum

DAD1 (FL-113) - sc-25557 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

DAD1 (N-20) - sc-12173 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-DAD1 antibody - ab23836 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-DAD1 antibody (ab23836) at 0.5 µg/mlLane 2 : Anti-DAD1 antibody (ab23836) at 1 µg/mlLane 3 : Anti-DAD1 antibody (ab23836) at 2 µg/mlLane 1 : HepG2 whole cell lysateLane 2 : HepG2 whole cell lysateLane 3 : HepG2 whole cell lysate

Anti-DAD1 antibody - ab116226 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab116226, at 2.5 µg/ml, staining DAD1 in formalin fixed, paraffin embedded Human prostate tissue by Immunohistochemistry. After incubation with the primary antibody, slides were incubated with biotinylated goat anti-rabbit IgG secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Anti-DAD1 antibody - C-terminal - ab173220 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DAD1 antibody - C-terminal (ab173220) at 1/100 dilution + WiDr cell line lysates at 35 µg

Anti-DAD1 Antibody (C-Terminus) IHC-plus™ - LS-B555 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DAD1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B555 concentration 5 ug/ml.

Anti-DAD1 Antibody (C-Terminus) - LS-C6389 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DAD1 Antibody (C-Terminus) - LS-C6390 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DAD1 Antibody (HRP) - LS-C183157 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DAD1 Antibody (FITC) - LS-C183158 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DAD1 Antibody (Biotin) - LS-C183159 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DAD1 Antibody (aa64-92, AP) - LS-C221987 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DAD1 Antibody (aa64-92, APC) - LS-C221988 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DAD1 Antibody (aa64-92) - LS-C159436 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DAD1 Antibody western blot of WiDr cell line lysates (35 ug/lane). The DAD1 antibody detected the DAD1 protein (arrow).

Anti-DAD1 Antibody (clone 2B4-C8) - LS-C197017 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2B4-C8
Detection limit for recombinant GST tagged DAD1 is 0.3 ng/ml as a capture antibody.

Anti-DAD1 Antibody (aa64-92, PE) - LS-C221989 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DAD1 Antibody (FITC) - LS-C210888 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 12. 4 kDa. Observed band size: 40 kDa.

Anti-DAD1 Antibody (HRP) - LS-C210887 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 12. 4 kDa. Observed band size: 40 kDa.

Anti-DAD1 Antibody (Biotin) - LS-C210889 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 12. 4 kDa. Observed band size: 40 kDa.

Anti-DAD1 Antibody (aa63-92) - LS-C320735 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DAD1 Antibody - LS-C210893 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 12. 4 kDa. Observed band size: 40 kDa.

DAD1 Antibody - NBP1-02946 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: DAD1 Antibody [NBP1-02946] - Staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

DAD1 Antibody - NBP1-77197 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DAD1 Antibody [NBP1-77197] - Analysis in human bladder tissue lysate (loaded 15ug/lane) with and without the blocking peptide.

DAD1 Antibody - NB600-669 from Novus Biologicals

Prices $279.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DAD1 Antibody [NB600-669] - Analysis of whole cell lysates from HepG2 human hepatocellular carcinoma cells probed with Rabbit anti Human DAD1

DAD1 Antibody - H00001603-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
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