| Gene Symbol |
DENND2A
|
| Entrez Gene |
27147
|
| Alt Symbol |
FAM31D, KIAA1277
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DENN/MADD domain containing 2A
|
| Other Description |
DENN domain-containing protein 2A
|
| Swissprots |
Q86XY0 Q1RMD5 C9JUI3 Q9ULE3
|
| Accessions |
EAW83954 Q9ULE3 AB033103 BAA86591 AK290056 BAF82745 AK297959 BAG60271 BC049193 AAH49193 BC115004 AAI15005 BC132875 AAI32876 BC144190 DA401015 XM_005249976 XP_005250033 XM_005249977 XP_005250034 XM_005249978 XP_005250035 XM_005249979 XP_005250036 XM_011516052 XP_011514354 XM_011516053 XP_011514355 XM_011516054 XP_011514356 XR_927456 NM_015689 NP_056504
|
| Function |
Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. May play a role in late endosomes back to trans-Golgi network/TGN transport. {ECO:0000269|PubMed:20937701}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20937701}. Note=Associated with actin filaments.
|