| Gene Symbol |
P2RX4
|
| Entrez Gene |
5025
|
| Alt Symbol |
P2X4, P2X4R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
purinergic receptor P2X, ligand gated ion channel, 4
|
| Other Description |
ATP receptor|ATP-gated cation channel protein|P2X purinoceptor 4|P2X receptor, subunit 4|purinergic receptor P2X, ligand-gated ion channel, 4|purinergic receptor P2X4|purinoceptor P2X4
|
| Swissprots |
Q5U090 O14722 F6RU17 Q9UBG9 Q5U089 E7EPF7 Q8N4N1 O00450 Q99571
|
| Accessions |
AAD00556 AAF06661 EAW98242 EAW98243 EAW98244 EAW98245 EAW98246 Q99571 AF000234 AAB58405 AF012903 AAB66834 AK225604 AK293599 BAH11544 AK293660 BAH11561 AK297704 BAH12651 AK301080 BAH13404 AK308549 AK308868 BC017458 BC033826 AAH33826 BC035845 BT019738 AAV38543 BT019739 AAV38544 BX402887 DQ851491 ABI31772 DQ890906 ABM81832 DQ894059 ABM84985 JF807485 AEC23355 JX471561 AFU91506 U83993 AAD00553 Y07684 CAA68948 XM_011538416 XP_011536718 XM_011538417 XP_011536719 XR_944559 NM_001256796 NP_001243725 NM_001261397 NP_001248326 NM_001261398 NP_001248327 NM_002560 NP_002551 NR_046372 NR_046373 NM_175567 NM_175568
|
| Function |
Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. {ECO:0000269|PubMed:10515189}.
|
| Subcellular Location |
Membrane {ECO:0000269|PubMed:10515189}; Multi-pass membrane protein {ECO:0000269|PubMed:10515189}.
|
| Top Pathways |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|
![Western Blot: P2RX4 Overexpression Lysate (Adult Normal) [NBP2-08102] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for P2RX4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26225_P2RX4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08102-img0001.jpg)