P2RX4

Gene Symbol P2RX4
Entrez Gene 5025
Alt Symbol P2X4, P2X4R
Species Human
Gene Type protein-coding
Description purinergic receptor P2X, ligand gated ion channel, 4
Other Description ATP receptor|ATP-gated cation channel protein|P2X purinoceptor 4|P2X receptor, subunit 4|purinergic receptor P2X, ligand-gated ion channel, 4|purinergic receptor P2X4|purinoceptor P2X4
Swissprots Q5U090 O14722 F6RU17 Q9UBG9 Q5U089 E7EPF7 Q8N4N1 O00450 Q99571
Accessions AAD00556 AAF06661 EAW98242 EAW98243 EAW98244 EAW98245 EAW98246 Q99571 AF000234 AAB58405 AF012903 AAB66834 AK225604 AK293599 BAH11544 AK293660 BAH11561 AK297704 BAH12651 AK301080 BAH13404 AK308549 AK308868 BC017458 BC033826 AAH33826 BC035845 BT019738 AAV38543 BT019739 AAV38544 BX402887 DQ851491 ABI31772 DQ890906 ABM81832 DQ894059 ABM84985 JF807485 AEC23355 JX471561 AFU91506 U83993 AAD00553 Y07684 CAA68948 XM_011538416 XP_011536718 XM_011538417 XP_011536719 XR_944559 NM_001256796 NP_001243725 NM_001261397 NP_001248326 NM_001261398 NP_001248327 NM_002560 NP_002551 NR_046372 NR_046373 NM_175567 NM_175568
Function Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. {ECO:0000269|PubMed:10515189}.
Subcellular Location Membrane {ECO:0000269|PubMed:10515189}; Multi-pass membrane protein {ECO:0000269|PubMed:10515189}.
Top Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction

P2X4 (H-40) - sc-28764 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
P2X4 (H-40): sc-28764. Western blot analysis of P2X4 expression in rat (A) and mouse (B) thymus tissue extracts.

P2X4 (N-15) - sc-15187 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
P2X4 (N-15): sc-15187. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing apical membrane staining of glandular cells.

P2X4 (C-15) - sc-15190 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-P2RX4 antibody - ab82329 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab82329 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab82329, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-P2RX4 antibody - ab76893 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-P2RX4 antibody (ab76893) at 1 µg/mlLane 1 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 2 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell Lysate Lane 3 : SK N BE (Human neuroblastoma) Whole Cell Lysate Lane 4 : SK N SH (Human neuroblastoma) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-P2RX4 / P2X4 Antibody (aa370-388) - LS-C17175 from LifeSpan Bioscience

Prices $465.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-P2RX4 / P2X4 Antibody (aa368-388) - LS-C313507 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-P2RX4 / P2X4 Antibody (aa35-84) - LS-C110051 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
P2RX4 / P2X4 antibody LS-C110051 Western blot of Fetal Muscle lysate.

Anti-P2RX4 / P2X4 Antibody - LS-C334869 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using P2RX4 antibody.

Anti-P2RX4 / P2X4 Antibody (aa367-380) - LS-C112758 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
P2RX4 antibody (0.3 ug/ml) staining of Human Kidney lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-P2RX4 / P2X4 Antibody (aa56-69) IHC-plus™ - LS-B9556 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-P2RX4 / P2X4 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9556 concentration 5 ug/ml.

P2X4 Antibody - NBP1-92239 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: P2X4 Antibody [NBP1-92239] - Analysis in human cell line SK-MEL-30.

P2X4 Antibody - NBP1-00141 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: P2X4 Antibody [NBP1-00141] - P2RX4 Antibody [NBP1-00141] - Analysis of P2RX4 in Human Kidney lysate (35ug protein in RIPA buffer) using NBP1-00141 at 0.3ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

P2X4 Antibody - H00005025-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: P2X4 Antibody [H00005025-B01P] - Analysis of P2RX4 expression in transfected 293T cell line by P2RX4 polyclonal antibody. Lane 1: P2RX4 transfected lysate(42.68 KDa). Lane 2: Non-transfected lysate.

P2X4 Antibody - NBP1-20177 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

P2X4 Antibody - H00005025-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: P2X4 Antibody [H00005025-D01P] - Analysis of P2RX4 expression in transfected 293T cell line by P2RX4 polyclonal antibody.Lane 1: P2RX4 transfected lysate(43.40 KDa).Lane 2: Non-transfected lysate.

Anti-P2RX4, (N-terminal) antibody produced in rabbit - SAB2103401 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-P2RX4, antibody produced in rabbit: <B>Cat. No. SAB2103401</B>: Immunoblotting analysis of P2RX4 in fetal muscle tissue lysate with P2RX4 anitbody at 1 μg/mL.

Anti-P2X4/P2X4R antibody produced in goat - SAB2500734 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-P2X4 / P2X4R: <B>Cat. No. SAB2500734</B>: (0.3 μg/mL) staining of Human Kidney lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-P2RX4 antibody produced in mouse - SAB1406208 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-P2RX4: <B>Cat. No. SAB1406208</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~42.7 kDa using P2RX4 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-P2RX4 antibody produced in rabbit - HPA039494 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-P2RX4: <B>Cat. No. HPA039494</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Anti-P2RX4 antibody produced in rabbit - SAB1401274 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-P2RX4, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401274</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~43.40 kDa using P2RX4 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-P2rx4 antibody produced in goat - SAB2502047 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-P2rx4<B>Cat. No. SAB2502047</B>: Immunoblotting (1 μg/mL) staining of Human Kidney lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

P2RX4 antibody - N-terminal region (ARP35512_P050) - ARP35512_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

P2X4--P2X4R-Antibody - AF1771a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1771a (0.3 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

P2rx4-mouse-Antibody-internal-region - AF3725a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3725a (1 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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