| Gene Symbol |
ANOS1
|
| Entrez Gene |
3730
|
| Alt Symbol |
ADMLX, HH1, HHA, KAL, KAL1, KALIG-1, KMS, WFDC19
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
anosmin 1
|
| Other Description |
Kallmann syndrome 1 sequence|Kallmann syndrome interval gene 1|Kallmann syndrome-1 sequence (anosmin-1)|WAP four-disulfide core domain 19|adhesion molecule-like X-linked|anosmin-1|kallmann syndrome protein
|
| Swissprots |
P23352 B2RPF8
|
| Accessions |
CAA57554 EAW98759 P23352 AI582702 BC137426 AAI37427 BC137427 AAI37428 CN417843 M97252 AAA59202 S60085 AAB20108 S60088 X60299 CAA42841 XM_005274501 XP_005274558 NM_000216 NP_000207
|
| Function |
Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells. {ECO:0000250, ECO:0000269|PubMed:19696444}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:8842728}; Peripheral membrane protein {ECO:0000269|PubMed:8842728}. Secreted {ECO:0000269|PubMed:8842728}. Note=Proteolytic cleavage may release it from the cell surface into the extracellular space.
|
| Tissue Specificity |
Expressed in the cerebellum (at protein level). {ECO:0000269|PubMed:12007408}.
|
![Western Blot: KAL1 Overexpression Lysate (Adult Normal) [NBL1-12120] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KAL1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7285_KAL1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12120-img0002.jpg)