Gene Symbol | ANOS1 |
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Entrez Gene | 3730 |
Alt Symbol | ADMLX, HH1, HHA, KAL, KAL1, KALIG-1, KMS, WFDC19 |
Species | Human |
Gene Type | protein-coding |
Description | anosmin 1 |
Other Description | Kallmann syndrome 1 sequence|Kallmann syndrome interval gene 1|Kallmann syndrome-1 sequence (anosmin-1)|WAP four-disulfide core domain 19|adhesion molecule-like X-linked|anosmin-1|kallmann syndrome protein |
Swissprots | P23352 B2RPF8 |
Accessions | CAA57554 EAW98759 P23352 AI582702 BC137426 AAI37427 BC137427 AAI37428 CN417843 M97252 AAA59202 S60085 AAB20108 S60088 X60299 CAA42841 XM_005274501 XP_005274558 NM_000216 NP_000207 |
Function | Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells. {ECO:0000250, ECO:0000269|PubMed:19696444}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:8842728}; Peripheral membrane protein {ECO:0000269|PubMed:8842728}. Secreted {ECO:0000269|PubMed:8842728}. Note=Proteolytic cleavage may release it from the cell surface into the extracellular space. |
Tissue Specificity | Expressed in the cerebellum (at protein level). {ECO:0000269|PubMed:12007408}. |
KALIG-1 CRISPR/Cas9 KO Plasmid (h) - sc-407717 from Santa Cruz Biotechnology
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KALIG-1 HDR Plasmid (h) - sc-407717-HDR from Santa Cruz Biotechnology
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KALIG-1 Double Nickase Plasmid (h) - sc-407717-NIC from Santa Cruz Biotechnology
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KALIG-1 Double Nickase Plasmid (h2) - sc-407717-NIC-2 from Santa Cruz Biotechnology
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KALIG-1 CRISPR Activation Plasmid (h) - sc-407717-ACT from Santa Cruz Biotechnology
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KALIG-1 CRISPR Activation Plasmid (h2) - sc-407717-ACT-2 from Santa Cruz Biotechnology
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KALIG-1 Lentiviral Activation Particles (h) - sc-407717-LAC from Santa Cruz Biotechnology
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KALIG-1 Lentiviral Activation Particles (h2) - sc-407717-LAC-2 from Santa Cruz Biotechnology
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KALIG siRNA (h) - sc-43036 from Santa Cruz Biotechnology
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KALIG shRNA Plasmid (h) - sc-43036-SH from Santa Cruz Biotechnology
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KALIG shRNA (h) Lentiviral Particles - sc-43036-V from Santa Cruz Biotechnology
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KAL1 RNAi - H00003730-R01 from Novus Biologicals
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MISSION® esiRNA - EHU111281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10889 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10889 from Sigma-Aldrich
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KAL1 siRNA (Human) - CRH2510 from Cohesion Biosciences
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KAL1, siRNA - MBS8216599 from MyBioSource
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shRNA set against Human KAL1 (NM_000216.2) - SHH322331 from Creative biogene
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Human KAL1 siRNA - orb263012 from Biorbyt
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KAL1 shRNA Plasmid (Human) - CHH2510 from Cohesion Biosciences
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KAL1 miRNA 3'UTR clone - MiUTR1H-05085 from Creative biogene
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