| Gene Symbol |
ARHGAP15
|
| Entrez Gene |
55843
|
| Alt Symbol |
BM046
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rho GTPase activating protein 15
|
| Other Description |
rho GTPase-activating protein 15|rho-type GTPase-activating protein 15
|
| Swissprots |
Q8IXX1 Q584N9 Q9NRL8 Q9NZ77 Q53SX9 Q9NZ91 Q53QZ3 Q6PJE6 Q53R36 Q53RD7 Q53RT6 Q86WP1
|
| Accessions |
AAX82009 AAX93158 AAX93160 AAX93245 AAY14811 AAY24215 EAX11587 EAX11588 EAX11589 EAX11590 Q53QZ3 AF212222 AAF87324 AF217507 AAF67618 AF217522 AAF67633 AK226014 AK303490 BAG64525 AK308219 AY219338 AAO34684 BC016701 AAH16701 BC038976 AAH38976 BP299206 XM_005263714 XP_005263771 XM_006712632 XP_006712695 XM_011511479 XP_011509781 XM_011511480 XP_011509782 XM_011511481 XP_011509783 XM_011511482 XP_011509784 XM_011511483 XP_011509785 XM_011511484 XP_011509786 NM_018460 NP_060930
|
| Function |
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction. {ECO:0000269|PubMed:12650940}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12650940}. Membrane {ECO:0000269|PubMed:12650940}; Peripheral membrane protein {ECO:0000269|PubMed:12650940}.
|
| Tissue Specificity |
Expressed in lung, liver and lymphoid cells. {ECO:0000269|PubMed:12650940}.
|
![Western Blot: ARHGAP15 Overexpression Lysate (Adult Normal) [NBL1-07666] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ARHGAP15.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5904_ARHGAP15%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07666-img0002.jpg)