Gene Symbol | VDAC2 |
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Entrez Gene | 7417 |
Alt Symbol | POR |
Species | Human |
Gene Type | protein-coding |
Description | voltage-dependent anion channel 2 |
Other Description | outer mitochondrial membrane protein porin 2|voltage-dependent anion-selective channel protein 2 |
Swissprots | Q5VWK1 Q7L3J5 Q9Y5I6 Q9BWK8 P45880 Q6IB40 Q5VWK3 |
Accessions | AAD40241 EAW54569 EAW54570 EAW54571 EAW54572 EAW54573 EAW54574 P45880 AK296635 BAG59237 AK315919 BAH14290 BC000165 AAH00165 BC012883 AAH12883 BC072407 AAH72407 BE545584 BU171142 CF122447 CR456964 CAG33245 DA608755 DQ890934 ABM81860 DQ894097 ABM85023 L06328 AAB59457 L08666 AAA60144 XM_006717961 XP_006718024 XM_011540128 XP_011538430 NM_001184783 NP_001171712 NM_001184823 NP_001171752 NM_003375 NP_003366 NR_033675 |
Function | Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective. |
Subcellular Location | Mitochondrion outer membrane {ECO:0000269|PubMed:7539795}. |
Tissue Specificity | Expressed in all tissues examined. |
Top Pathways | Huntington's disease, Calcium signaling pathway, HTLV-I infection, cGMP-PKG signaling pathway |
Human VDAC2 full length protein - ab152792 from Abcam
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Human VDAC2 full length protein - ab152793 from Abcam
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VDAC2 Antibody Blocking Peptide - LS-E25701 from LifeSpan Bioscience
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VDAC2 Antibody Blocking Peptide - LS-E26165 from LifeSpan Bioscience
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VDAC2 Antibody Blocking Peptide - LS-E12495 from LifeSpan Bioscience
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VDAC2 Recombinant Protein - H00007417-P01 from Novus Biologicals
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Recombinant Human VDAC2 Protein - H00007417-P02 from Novus Biologicals
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VDAC2-Antibody-Center-Blocking-Peptide - BP18807c from Abgent, a WuXi AppTec company
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VDAC2 (C Terminus) blocking peptide - GTX89782-PEP from GeneTex
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VDAC2 (Internal) blocking peptide - GTX89279-PEP from GeneTex
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VDAC2 Protein Lysate (APL10425) - APL10425 from Aviva Systems Biology
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VDAC2 Blocking Peptide - 33R-5772 from Fitzgerald
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VDAC2 Blocking Peptide - 33R-9629 from Fitzgerald
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VDAC2 Peptide - AC21-0531-P from Abcore
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VDAC2 Peptide - AC21-0995-P from Abcore
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VDAC2 - H00007417-P01-02 from Acris Antibodies
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VDAC2 - H00007417-P02 from Acris Antibodies
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VDAC2 - H00007417-P02-10 from Acris Antibodies
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VDAC2 - H00007417-P02-25 from Acris Antibodies
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VDAC2 Peptide - 46-570P from ProSci
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VDAC2 Peptide - 46-569P from ProSci
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VDAC2 fusion protein - Ag2266 from Proteintech Group
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Recombinant Human VDAC2, GST-tagged - VDAC2-3658H from Creative Biomart
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Voltage-dependent anion-selective channel protein 2 (VDAC2), Recombinant Protein - MBS959855 from MyBioSource
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VDAC2, Peptide - MBS428292 from MyBioSource
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