Ubxn1

Gene Symbol Ubxn1
Entrez Gene 225896
Alt Symbol 2B28, 4930455J02Rik, D19Ertd721e, T25529
Species Mouse
Gene Type protein-coding
Description UBX domain protein 1
Other Description SAPK substrate protein 1|UBA/UBX 33.3 kDa protein|UBX domain-containing protein 1|mY33K|protein 2B28
Swissprots Q922Y1 Q3UCP8
Accessions EDL33390 EDL33391 Q922Y1 AK015468 AK150442 BAE29564 AK159708 AK172428 AK185583 BC006701 AAH06701 XM_006526922 XP_006526985 NM_146093 NP_666205
Function Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer (By similarity) Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. Involved in ubiquitin-proteasome systems. {ECO:0000250, ECO:0000269|PubMed:16709668}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15944415}.

Recombinant Mouse UBX domain-containing protein 1(Ubxn1) - CSB-YP849734MO CSB-EP849734MO CSB-BP849734MO CSB-MP849734MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse UBXN1 Protein - UBXN1-17769M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse
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