| Gene Symbol | INIP |
|---|---|
| Entrez Gene | 616784 |
| Alt Symbol | C8H9orf80, C9orf80, SSBIP1 |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | INTS3 and NABP interacting protein |
| Other Description | INTS3- and NABP-interacting protein|SOSS complex subunit C|SOSS-C|SSB-interacting protein 1|sensor of single-strand DNA complex subunit C|sensor of ssDNA subunit C|single-stranded DNA-binding protein-interacting protein 1 |
| Swissprots | Q2NKT2 |
| Accessions | DAA26475 Q2NKT2 BC111656 AAI11657 NM_001078064 NP_001071532 |
| Function | Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single- stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination- dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000250}. Note=Localizes to nuclear foci following DNA damage. {ECO:0000250}. |