Gene Symbol | INIP |
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Entrez Gene | 616784 |
Alt Symbol | C8H9orf80, C9orf80, SSBIP1 |
Species | Bovine |
Gene Type | protein-coding |
Description | INTS3 and NABP interacting protein |
Other Description | INTS3- and NABP-interacting protein|SOSS complex subunit C|SOSS-C|SSB-interacting protein 1|sensor of single-strand DNA complex subunit C|sensor of ssDNA subunit C|single-stranded DNA-binding protein-interacting protein 1 |
Swissprots | Q2NKT2 |
Accessions | DAA26475 Q2NKT2 BC111656 AAI11657 NM_001078064 NP_001071532 |
Function | Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single- stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination- dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Note=Localizes to nuclear foci following DNA damage. {ECO:0000250}. |
Recombinant Bovine SOSS complex subunit C(SSBIP1) - CSB-YP646759BO CSB-EP646759BO CSB-BP646759BO CSB-MP646759BO from Cusabio
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SOSS complex subunit C (SSBIP1), Recombinant Protein - MBS1350904 from MyBioSource
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