ICAM1

Gene Symbol ICAM1
Entrez Gene 3383
Alt Symbol BB2, CD54, P3.58
Species Human
Gene Type protein-coding
Description intercellular adhesion molecule 1
Other Description ICAM-1|cell surface glycoprotein P3.58|intercellular adhesion molecule 1 (CD54), human rhinovirus receptor|major group rhinovirus receptor
Swissprots Q5NKV7 P05362 Q96B50 B2R6M3
Accessions AAA52710 AAB51145 AAO30128 CAA40441 CAA41977 EAW84086 EAW84087 P05362 AF340038 AAQ14901 AF340039 AAQ14902 AK130659 AK298054 BAG60348 AK298983 BAG61077 AK301412 BAG62944 AK312636 BAG35520 BC015969 AAH15969 BG149901 BP346334 BT006854 AAP35500 DQ890615 ABM92232 DQ893785 ABM84711 J03132 AAA52709 M24283 AAA52708 M55024 AAA60392 M55038 AAA60393 M55091 M55100 S82847 AAB46863 X06990 CAA30051 NM_000201 NP_000192
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. {ECO:0000269|PubMed:11173916, ECO:0000269|PubMed:17875742, ECO:0000269|PubMed:1968231, ECO:0000269|PubMed:2538243}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Epstein-Barr virus infection, Influenza A, TNF signaling pathway, Natural killer cell mediated cytotoxicity, HTLV-I infection

CD54/ICAM-1 Antibody - 4915 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Ramos, A549 and Raji cells, untreated (-) or TNF-α-treated (+), using CD54/ICAM-1 Antibody.

ICAM-1 (M-19) - sc-1511 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ICAM-1 (M-19): sc-1511. Western blot analysis of ICAM-1 expression in mouse heart extract (A) and RAW 264.7 (B), HeLa (C) and SK-N-MC (D) whole cell lysates.

ICAM-1 (H-4) - sc-390483 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ICAM-1 (H-4): sc-390483. Western blot analysis of ICAM-1 expression in HeLa whole cell lysate.

ICAM-1 (G-5) - sc-8439 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ICAM-1 (G-5) PE: sc-8439 PE. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-2867.

ICAM-1 (H-85) - sc-366317 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ICAM-1 (H-108) - sc-7891 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ICAM-1 (H-108): sc-7891. Western blot analysis of ICAM-1 expression in HeLa whole cell lysate.

ICAM-1 (15.2) - sc-107 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ICAM-1 (15.2): sc-107. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane staining.

ICAM-1 (6.5B5) - sc-18853 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ICAM-1 (6.5B5): sc-18853. Western blot analysis of ICAM-1 expression in Raji (A), U266 (B) and SK-MEL-28 (C) whole cell lysates under non-reducing conditions.

ICAM-1 (LB-2) - sc-18908 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ICAM-1 (LB-2): sc-18908. Western blot analysis of ICAM-1 expression in TF-1 whole cell lysate.

ICAM-1 (P2A4) - sc-18839 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ICAM-1 (P2A4): sc-18839. Western blot analysis of ICAM-1 expression in Raji (A), U266 (B) and SK-MEL-28 (C) whole cell lysates under non-reducing conditions.

ICAM-1 (E-15) - sc-31724 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ICAM-1 (K-18) - sc-31725 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ICAM-1 (P1W16) - sc-53336 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ICAM-1 (P1W16): sc-53336. Indirect FCM analysis of human peripheral blood leukocytes stained with ICAM-1 (P1W16), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877

ICAM-1 (2Q710) - sc-71292 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ICAM-1 (2Q710): sc-71292. Western blot analysis of ICAM-1 expression in non-transfected: sc-117752 (A) and human ICAM-1 transfected: sc-176625 (B) 293T whole cell lysates.

ICAM-1 (28) - sc-135946 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
ICAM-1 (28): sc-135946. Western blot analysis of ICAM-1 expression in HCT-8 whole cell lysate.

p-ICAM-1 (Tyr 512) - sc-101702 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-ICAM-1 (Tyr 512): sc-101702. Western blot analysis of phosphorylated ICAM-1 expression in untreated (A), TNF-α-treated (B) and PMA-treated (C) HUVEC whole cell lysates.

Anti-ICAM1 (phospho Y512) antibody - ab51033 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ICAM1 (phospho Y512) antibody (ab51033) at 1/500 dilutionLane 1 : Hela cells treated with TNF alpha with immunizing peptideLane 2 : Hela cells treated with TNF alpha

Anti-ICAM1 antibody - ab124759 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ICAM1 antibody (ab124759) at 1 µg/mlLane 1 : RAW 264.7 (Mouse leukaemic monocyte macrophage cell line) Whole Cell LysateLane 2 : C2C12 (Mouse myoblast cell line) Whole Cell LysateLane 3 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLane 4 : HUVEC (Human Umbilical Vein Endothelial Cell) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-ICAM1 antibody - ab170497 from Abcam

Prices $372.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ICAM1 antibody - ab153749 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ICAM1 antibody (ab153749) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-ICAM1 antibody - ab89378 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Left panel: ab89378 at 1/100 dilution staining ICAM1 in formalin-fixed, paraffin-embedded Human tonsil tissue by immunohistochemistry .  Right panel: same, after pre-treatment with the immunizing peptide.

Anti-ICAM1 antibody - ab101275 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Detection of ICAM1 in Immunoprecipitates of HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab101275 at 3 µg/mg lysate for IP (Lane 1). An anti-ICAM1 antibody which recognizes an upstream epitope was used at 0.4 µg/ml for subsequent WB detection. Lane 2 represents control IgG IP. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-ICAM1 antibody - ab157748 from Abcam

Host Sheep
Clonality Polyclonal

Anti-ICAM1 antibody [15.2] - ab20 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 15.2
All lanes : Anti-ICAM1 antibody [15.2] (ab20) at 5 µg/mlLane 1 : SK N BE (Human neuroblastoma) Whole Cell Lysate Lane 2 : Saos 2 (Human epithelial-like osteosarcoma cell line) Whole Cell Lysate Lane 3 : HT 1080 (Human fibrosarcoma) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Anti-ICAM1 antibody [15.2] (Biotin) - ab19770 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 15.2
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