| Gene Symbol |
CLVS1
|
| Entrez Gene |
157807
|
| Alt Symbol |
CRALBPL, RLBP1L1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
clavesin 1
|
| Other Description |
clavesin-1|retinaldehyde binding protein 1-like 1|retinaldehyde-binding protein 1-like 1
|
| Swissprots |
B2R7M5 Q8NB32 C8UZT3 Q8IUQ0
|
| Accessions |
EAW86838 EAW86839 Q8IUQ0 AF445194 AAP97323 AK091641 AK094567 AK125153 AK313040 BAG35872 AY094971 AAM15733 BC042617 AAH42617 BC048992 BK006899 DAA06536 DA217517 HQ448548 ADQ33027 XM_011517470 XP_011515772 XM_011517471 XP_011515773 XM_011517472 XP_011515774 XM_011517473 XP_011515775 XM_011517474 XP_011515776 NM_173519 NP_775790
|
| Function |
Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). {ECO:0000250, ECO:0000269|PubMed:19651769}.
|
| Subcellular Location |
Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. Early endosome membrane {ECO:0000269|PubMed:19651769}; Peripheral membrane protein {ECO:0000269|PubMed:19651769}.
|
| Tissue Specificity |
Expressed mainly in the brain. {ECO:0000269|PubMed:16802092}.
|