Gene Symbol | CLVS1 |
---|---|
Entrez Gene | 157807 |
Alt Symbol | CRALBPL, RLBP1L1 |
Species | Human |
Gene Type | protein-coding |
Description | clavesin 1 |
Other Description | clavesin-1|retinaldehyde binding protein 1-like 1|retinaldehyde-binding protein 1-like 1 |
Swissprots | B2R7M5 Q8NB32 C8UZT3 Q8IUQ0 |
Accessions | EAW86838 EAW86839 Q8IUQ0 AF445194 AAP97323 AK091641 AK094567 AK125153 AK313040 BAG35872 AY094971 AAM15733 BC042617 AAH42617 BC048992 BK006899 DAA06536 DA217517 HQ448548 ADQ33027 XM_011517470 XP_011515772 XM_011517471 XP_011515773 XM_011517472 XP_011515774 XM_011517473 XP_011515775 XM_011517474 XP_011515776 NM_173519 NP_775790 |
Function | Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). {ECO:0000250, ECO:0000269|PubMed:19651769}. |
Subcellular Location | Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. Early endosome membrane {ECO:0000269|PubMed:19651769}; Peripheral membrane protein {ECO:0000269|PubMed:19651769}. |
Tissue Specificity | Expressed mainly in the brain. {ECO:0000269|PubMed:16802092}. |
CRALBPL CRISPR/Cas9 KO Plasmid (h) - sc-414774 from Santa Cruz Biotechnology
|
||||||||
CRALBPL HDR Plasmid (h) - sc-414774-HDR from Santa Cruz Biotechnology
|
||||||||
CRALBPL Double Nickase Plasmid (h) - sc-414774-NIC from Santa Cruz Biotechnology
|
||||||||
CRALBPL Double Nickase Plasmid (h2) - sc-414774-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CRALBPL CRISPR Activation Plasmid (h) - sc-414774-ACT from Santa Cruz Biotechnology
|
||||||||
CRALBPL CRISPR Activation Plasmid (h2) - sc-414774-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CRALBPL Lentiviral Activation Particles (h) - sc-414774-LAC from Santa Cruz Biotechnology
|
||||||||
CRALBPL Lentiviral Activation Particles (h2) - sc-414774-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CRALBPL siRNA (h) - sc-77860 from Santa Cruz Biotechnology
|
||||||||
CRALBPL shRNA Plasmid (h) - sc-77860-SH from Santa Cruz Biotechnology
|
||||||||
CRALBPL shRNA (h) Lentiviral Particles - sc-77860-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU133071 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN6276 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6276 from Sigma-Aldrich
|
||||||||
CLVS1 siRNA (Human) - CRJ5837 from Cohesion Biosciences
|
||||||||
CLVS1 - MBS8234737 from MyBioSource
|
||||||||
shRNA set against Human CLVS1 (NM_173519.2) - SHH265805 from Creative biogene
|
||||||||
CLVS1 shRNA Plasmid (Human) - CHJ5837 from Cohesion Biosciences
|
||||||||
CLVS1 miRNA 3'UTR clone - MiUTR4H-TG02199 from Creative biogene
|