EFNB2

Gene Symbol	EFNB2
Entrez Gene	1948
Alt Symbol	EPLG5, HTKL, Htk-L, LERK5
Species	Human
Gene Type	protein-coding
Description	ephrin-B2
Other Description	HTK ligand|LERK-5|eph-related receptor tyrosine kinase ligand 5|ligand of eph-related kinase 5
Swissprots	P52799 Q5JV56
Accessions	CAD91556 EAX09085 P52799 BC069342 AAH69342 BC074856 AAH74856 BC074857 AAH74857 BC105955 AAI05956 BC105956 AAI05957 BC105957 AAI05958 BG741114 BQ029549 BQ433342 BQ708550 BU622947 CB998384 DR004737 HQ448461 ADQ32941 L38734 AAC41752 U16797 AAA99707 U81262 AAD03786 NM_004093 NP_004084
Function	Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons. {ECO:0000269|PubMed:12734395}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Lung and kidney.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse EFNB2 / Ephrin B2 ELISA Kit (Sandwich ELISA) - LS-F6974 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Human EFNB2 / Ephrin B2 ELISA Kit (Sandwich ELISA) - LS-F6952 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Ephrin B2 (EFNB2), Human, ELISA Kit - SEE112Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.053ng/mL Range 0.156-10ng/mL

Ephrin-B2 (EFNB2), Human, ELISA kit - CSB-EL007466HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

ephrin-B2, ELISA Kit - MBS916324 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Ephrin B2 (EFNB2), ELISA Kit - MBS2024205 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.054ng/mL. Range 0.156-10ng/mL.

Ephrin B2 (EFNB2), ELISA Kit - MBS2020532 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.054ng/mL. Range 0.156-10ng/mL

ELISA Kit for Ephrin B2 (EFNB2) - SEE112Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.059ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Ephrin B2 (EFNB2) - SEE112Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Ephrin-B2(EFNB2) ELISA kit - CSB-EL007466HU from Cusabio Category ELISA Kit Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

ELISA Kit for Ephrin B2 (EFNB2) - SEE112Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.059ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Ephrin B2 (EFNB2), Human, ELISA Kit - DL-EFNB2-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human EFNB2 ELISA Kit - abx570864 from Abbexa Category ELISA Kit Sensitivity 0.053 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human Ephrin-B2 (EFNB2) ELISA Kit - EKC33592 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Human EFNB2 ELISA Kit - E013326 from Biobool Category ELISA Kit Sensitivity Typically less than 0.059ng/mL.

EFNB2 ELISA Kit (Human) (OKCD00417) - OKCD00417 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.057 ng/mL Range 0.156-10 ng/mL

EFNB2 ELISA Kit (Human) (OKDD00250) - OKDD00250 from Aviva Systems Biology Category ELISA Kit Prices $580.00 Sizes 96 wells Sensitivity < 0.053 ng/mL Range 0.156-10 ng/mL

anti-EFNB2 antibody - ARG65294 from Arigo Biolaboratories Category ELISA Kit

Human Ephrin-B2 (EFNB2) ELISA Kit - AE61710HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.057 ng/mL Range 0.156-10 ng/mL

Ephrin B2 (EFNB2), ELISA Kit - MBS451569 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.053ng/mL Range 0.156-10ng/mL

Ephrin B2 (EFNB2), ELISA Kit - MBS9374570 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human EFNB2 ELISA Kit - orb407600 from Biorbyt Category ELISA Kit Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

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