| Gene Symbol |
Mcoln1
|
| Entrez Gene |
94178
|
| Alt Symbol |
2210015I05Rik, TRPML1, mucolipidin
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
mucolipin 1
|
| Other Description |
mucolipin-1
|
| Swissprots |
Q99J21
|
| Accessions |
EDL21910 EDL21911 EDL21912 Q99J21 AF302009 AAL58667 AK008732 AK028385 BAC25922 AK032531 AK034471 BAC28719 AK038594 AK049606 BAC33838 AK195153 AK203892 BC005651 AAH05651 BC020377 XR_378673 NM_053177 NP_444407
|
| Function |
Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Late endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed, with the highest expression in brain, liver and kidney. {ECO:0000269|PubMed:11897010}.
|
| Top Pathways |
Lysosome
|