| Gene Symbol |
ARPC5
|
| Entrez Gene |
10092
|
| Alt Symbol |
ARC16, dJ127C7.3, p16-Arc
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
actin related protein 2/3 complex, subunit 5, 16kDa
|
| Other Description |
Arp2/3 protein complex subunit p16|actin-related protein 2/3 complex subunit 5|arp2/3 complex 16 kDa subunit
|
| Swissprots |
O15511 A6NEC4 Q6PG42
|
| Accessions |
EAW91163 EAW91164 O15511 AF006088 AAB64193 AF017807 AAB70561 AI148784 AK095424 BAG53053 AK129598 BC057237 AAH57237 BC071857 AAH71857 BC152789 AAI52790 BI758106 CN291383 HQ447728 ADQ32213 NM_001270439 NP_001257368 NM_005717 NP_005708
|
| Function |
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9230079}. Cell projection {ECO:0000269|PubMed:9230079}.
|
| Top Pathways |
Pathogenic Escherichia coli infection, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton
|