Gene Symbol | ARPC5 |
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Entrez Gene | 10092 |
Alt Symbol | ARC16, dJ127C7.3, p16-Arc |
Species | Human |
Gene Type | protein-coding |
Description | actin related protein 2/3 complex, subunit 5, 16kDa |
Other Description | Arp2/3 protein complex subunit p16|actin-related protein 2/3 complex subunit 5|arp2/3 complex 16 kDa subunit |
Swissprots | O15511 A6NEC4 Q6PG42 |
Accessions | EAW91163 EAW91164 O15511 AF006088 AAB64193 AF017807 AAB70561 AI148784 AK095424 BAG53053 AK129598 BC057237 AAH57237 BC071857 AAH71857 BC152789 AAI52790 BI758106 CN291383 HQ447728 ADQ32213 NM_001270439 NP_001257368 NM_005717 NP_005708 |
Function | Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9230079}. Cell projection {ECO:0000269|PubMed:9230079}. |
Top Pathways | Pathogenic Escherichia coli infection, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton |
p16-ARC CRISPR/Cas9 KO Plasmid (h) - sc-403469 from Santa Cruz Biotechnology
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p16-ARC HDR Plasmid (h) - sc-403469-HDR from Santa Cruz Biotechnology
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p16-ARC Double Nickase Plasmid (h) - sc-403469-NIC from Santa Cruz Biotechnology
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p16-ARC Double Nickase Plasmid (h2) - sc-403469-NIC-2 from Santa Cruz Biotechnology
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p16-ARC CRISPR Activation Plasmid (h) - sc-403469-ACT from Santa Cruz Biotechnology
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p16-ARC CRISPR Activation Plasmid (h2) - sc-403469-ACT-2 from Santa Cruz Biotechnology
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p16-ARC Lentiviral Activation Particles (h) - sc-403469-LAC from Santa Cruz Biotechnology
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p16-ARC Lentiviral Activation Particles (h2) - sc-403469-LAC-2 from Santa Cruz Biotechnology
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p16-ARC siRNA (h) - sc-62733 from Santa Cruz Biotechnology
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p16-ARC shRNA Plasmid (h) - sc-62733-SH from Santa Cruz Biotechnology
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p16-ARC shRNA (h) Lentiviral Particles - sc-62733-V from Santa Cruz Biotechnology
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ARPC5 RNAi - H00010092-R01 from Novus Biologicals
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MISSION® esiRNA - EHU093801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3531 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09608 from Sigma-Aldrich
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ARPC5 siRNA (Human) - CRH6800 from Cohesion Biosciences
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p16-ARC siRNA (r) - sc-270591 from Santa Cruz Biotechnology
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p16-ARC shRNA Plasmid (r) - sc-270591-SH from Santa Cruz Biotechnology
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p16-ARC shRNA (r) Lentiviral Particles - sc-270591-V from Santa Cruz Biotechnology
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ARPC5 - MBS8240691 from MyBioSource
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p16-ARC CRISPR/Cas9 KO Plasmid (h2) - sc-403469-KO-2 from Santa Cruz Biotechnology
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p16-ARC HDR Plasmid (h2) - sc-403469-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ARPC5 (NM_005717.3) - SHH240666 from Creative biogene
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ARPC5 shRNA Plasmid (Human) - CHH6800 from Cohesion Biosciences
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