| Gene Symbol | CNOT4 |
|---|---|
| Entrez Gene | 4850 |
| Alt Symbol | CLONE243, NOT4, NOT4H |
| Species | Human |
| Gene Type | protein-coding |
| Description | CCR4-NOT transcription complex, subunit 4 |
| Other Description | CCR4-NOT transcription complex subunit 4|CCR4-associated factor 4|E3 ubiquitin-protein ligase CNOT4|NOT4 (negative regulator of transcription 4, yeast) homolog|potential transcriptional repressor NOT4Hp |
| Swissprots | E7ET38 Q8NCL0 O95339 F8VQP3 B7Z6I4 O95627 Q9NPQ1 Q8IYM7 Q9NZN6 O95628 |
| Accessions | EAW83849 EAW83850 EAW83851 EAW83852 EAW83853 EAW83854 O95628 AF091094 AAC72963 AF180475 AAF29829 AK074493 BAG51961 AK074671 BAC11125 AK300365 BAH13270 AK314540 AL389980 CAB97536 AL519669 BC035590 AAH35590 CA396599 DA247976 U71267 AAD00179 U71268 AAD00180 XM_011516252 XP_011514554 NM_001008225 NP_001008226 NM_001190847 NP_001177776 NM_001190848 NP_001177777 NM_001190849 NP_001177778 NM_001190850 NP_001177779 NM_013316 NP_037448 |
| Function | Has E3 ubiquitin ligase activity. Involved in activation of the JAK/STAT pathway. {ECO:0000269|PubMed:11823428, ECO:0000269|PubMed:22159038}. |
| Subcellular Location | Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. |
| Top Pathways | RNA degradation |