TP53INP2

Gene Symbol TP53INP2
Entrez Gene 58476
Alt Symbol C20orf110, DOR, PINH, dJ1181N3.1
Species Human
Gene Type protein-coding
Description tumor protein p53 inducible nuclear protein 2
Other Description PIG-U|diabetes and obesity regulated|diabetes and obesity-regulated|p53-inducible protein U|tumor protein p53-inducible nuclear protein 2
Swissprots Q9NU00 Q5JX64 Q8IYL5 Q8IXH6 A8K8S8 E1P5P6
Accessions EAW76256 EAW76257 EAW76258 Q8IXH6 AJ297792 CAC82592 AK025412 AK027153 AK292443 BAF85132 AL122050 AL137597 AY422170 AAR23799 BC035639 AAH35639 XM_005260476 XP_005260533 XM_006723841 XP_006723904 XM_011528952 XP_011527254 XM_011528953 XP_011527255 NM_021202 NP_067025
Function Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. {ECO:0000269|PubMed:18030323, ECO:0000269|PubMed:19056683, ECO:0000269|PubMed:22470510}.
Subcellular Location Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Note=Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.

TP53INP2 (G-15) - sc-85972 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TP53INP2 (P-18) - sc-85973 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TP53INP2 antibody - ab129784 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab129784, at a 1/50 dilution, staining TP53INP2 in paraffin embedded Human breast carcinoma tissue by Immunohistochemistry. Left image: no immunizing peptide Right image: with immunizing peptide

Anti-TP53INP2 Antibody (Biotin) - LS-C180664 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 Antibody (DY650) - LS-C180665 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 Antibody (DY550) - LS-C180667 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 Antibody (DY488) - LS-C180666 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 Antibody (C-Terminus, AP) - LS-C246164 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 Antibody (C-Terminus, APC) - LS-C246165 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 Antibody (C-Terminus, PE) - LS-C246168 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 Antibody (C-Terminus, FITC) - LS-C246166 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 Antibody (C-Terminus, Azide-free, HRP) - LS-C247930 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 Antibody (aa1-50) - LS-C119137 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using TP53INP2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-TP53INP2 Antibody (C-Terminus) - LS-C117094 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TP53INP2 antibody LS-C117094 Western blot of Fetal Heart lysate.

Anti-TP53INP2 Antibody - LS-C180111 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: TP53INP2 Antibody - Staining of TP53INP2 in mouse prostate.

Anti-TP53INP2 antibody produced in rabbit - HPA052974 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TP53INP2:<B>Cat. No. HPA052974</B>: Immunohistochemical staining of human colon shows strong cytoplasmic positivity in goblet cells.

Anti-TP53INP2 antibody produced in rabbit - SAB2107358 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TP53INP2: <B>Cat. No. SAB2107358</B>: Western blot analysis of TP53INP2 with TP53INP2 (tumor protein p53 inducible nuclear protein 2) antibody against the C terminal of TP53INP2 (50 μg) antibody at 1.0 μg/mL.

TP53INP2 antibody - C-terminal region (ARP58965_P050) - ARP58965_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TP53INP2 antibody - orb163036 from Biorbyt

Prices $281.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

TP53INP2 antibody - 70R-9644 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 antibody - STJ96071 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

TP53INP2 Polyclonal Antibody - PA003598-C11320 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

TP53INP2 Antibody - GWB-MV452B from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TP53INP2 (internal region) polyclonal antibody - DPABH-24127 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

TP53INP2, Polyclonal Antibody - MBS623501 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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