TP53INP2

Gene Symbol TP53INP2
Entrez Gene 58476
Alt Symbol C20orf110, DOR, PINH, dJ1181N3.1
Species Human
Gene Type protein-coding
Description tumor protein p53 inducible nuclear protein 2
Other Description PIG-U|diabetes and obesity regulated|diabetes and obesity-regulated|p53-inducible protein U|tumor protein p53-inducible nuclear protein 2
Swissprots Q9NU00 Q5JX64 Q8IYL5 Q8IXH6 A8K8S8 E1P5P6
Accessions EAW76256 EAW76257 EAW76258 Q8IXH6 AJ297792 CAC82592 AK025412 AK027153 AK292443 BAF85132 AL122050 AL137597 AY422170 AAR23799 BC035639 AAH35639 XM_005260476 XP_005260533 XM_006723841 XP_006723904 XM_011528952 XP_011527254 XM_011528953 XP_011527255 NM_021202 NP_067025
Function Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. {ECO:0000269|PubMed:18030323, ECO:0000269|PubMed:19056683, ECO:0000269|PubMed:22470510}.
Subcellular Location Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Note=Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.

TP53INP2 CRISPR/Cas9 KO Plasmid (h) - sc-405261 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TP53INP2 HDR Plasmid (h) - sc-405261-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TP53INP2 Double Nickase Plasmid (h) - sc-405261-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TP53INP2 Double Nickase Plasmid (h2) - sc-405261-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TP53INP2 CRISPR Activation Plasmid (h) - sc-405261-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TP53INP2 CRISPR Activation Plasmid (h2) - sc-405261-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TP53INP2 Lentiviral Activation Particles (h) - sc-405261-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TP53INP2 Lentiviral Activation Particles (h2) - sc-405261-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TP53INP2 siRNA (h) - sc-76717 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TP53INP2 shRNA Plasmid (h) - sc-76717-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TP53INP2 shRNA (h) Lentiviral Particles - sc-76717-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN21849 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21849 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TP53INP2 siRNA (Human) - CRJ1710 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TP53INP2 - MBS8230130 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TP53INP2 CRISPR/Cas9 KO Plasmid (h2) - sc-405261-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TP53INP2 HDR Plasmid (h2) - sc-405261-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human TP53INP2 (NM_021202.1) - SHH433112 from Creative biogene

Category siRNA
Species Reactivities Human

Human TP53INP2 siRNA - orb272211 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TP53INP2 shRNA Plasmid (Human) - CHJ1710 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TP53INP2 miRNA 3'UTR clone - MiUTR1H-10658 from Creative biogene

Species Reactivities Human
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