| Gene Symbol |
NT5C1A
|
| Entrez Gene |
84618
|
| Alt Symbol |
CN-I, CN-IA, CN1, CN1A, CNI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
5'-nucleotidase, cytosolic IA
|
| Other Description |
AMP-specific 5'-NT|cytosolic 5' nucleotidase, type 1A|cytosolic 5'-nucleotidase 1A|cytosolic 5'-nucleotidase IA
|
| Swissprots |
Q9BWT8 Q5TG98 Q9BXI3 Q3SYB9
|
| Accessions |
EAX07259 Q9BXI3 AF331801 AAK01294 AY028778 AAK30000 BC103879 AAI03880 BC103880 AAI03881 NM_032526 NP_115915
|
| Function |
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. {ECO:0000269|PubMed:11133996}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas. {ECO:0000269|PubMed:11133996}.
|
| Top Pathways |
Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism
|