Gene Symbol | NT5C1A |
---|---|
Entrez Gene | 84618 |
Alt Symbol | CN-I, CN-IA, CN1, CN1A, CNI |
Species | Human |
Gene Type | protein-coding |
Description | 5'-nucleotidase, cytosolic IA |
Other Description | AMP-specific 5'-NT|cytosolic 5' nucleotidase, type 1A|cytosolic 5'-nucleotidase 1A|cytosolic 5'-nucleotidase IA |
Swissprots | Q9BWT8 Q5TG98 Q9BXI3 Q3SYB9 |
Accessions | EAX07259 Q9BXI3 AF331801 AAK01294 AY028778 AAK30000 BC103879 AAI03880 BC103880 AAI03881 NM_032526 NP_115915 |
Function | Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. {ECO:0000269|PubMed:11133996}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas. {ECO:0000269|PubMed:11133996}. |
Top Pathways | Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism |