RGCC

Gene Symbol	RGCC
Entrez Gene	28984
Alt Symbol	C13orf15, RGC-32, RGC32, bA157L14.2
Species	Human
Gene Type	protein-coding
Description	regulator of cell cycle
Other Description	regulator of cell cycle RGCC\|response gene to complement 32 protein
Swissprots	Q6NZ48 Q9UL69 Q9H4X1
Accessions	EAX08663 EAX08664 Q9H4X1 AF036549 AAF04336 AK091099 AK095079 BC038706 BC066334 AAH66334 BU679672 DB451897 XM_011535051 XP_011533353 XR_941564 XR_941565 NM_014059 NP_054778
Function	Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation. {ECO:0000269\|PubMed:11687586, ECO:0000269\|PubMed:17146433, ECO:0000269\|PubMed:19158077, ECO:0000269\|PubMed:22163048}.
Subcellular Location	Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic in unstimulated cells. Nuclear after activation by complement. Associated with the centrosome during prometaphase and metaphase.
Tissue Specificity	Detected in brain, heart and liver (at protein level). Highly expressed in liver, skeletal muscle, kidney and pancreas. Detected at lower levels in heart, brain and placenta. Detected in aorta endothelial cells. Overexpressed in colon, breast, prostate, bladder, lung, and ovarian cancer tissues. {ECO:0000269\|PubMed:11687586, ECO:0000269\|PubMed:15713436}.

RGC32 (C-14) - sc-84222 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

RGC32 (D-16) - sc-84223 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

Anti-C13orf15 antibody - ab103669 from Abcam

Host	Rabbit
Clonality	Polyclonal

Anti-C13orf15 antibody (ab103669) at 1/100 dilution + HL-60 cell line lysates at 35 µg

Anti-RGCC Antibody (Internal) - LS-C345838 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of RGCC Antibody with human MCF7 Whole Cell lysate.

RGC32 Antibody - NBP1-90039 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: RGC32 Antibody [NBP1-90039] - Analysis in human lung tissue.

RGC32 Antibody - 44450002 from Novus Biologicals

Prices	$299.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

RGC32 Antibody (3B9) - H00028984-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3B9

Immunocytochemistry/Immunofluorescence: RGC32 Antibody (3B9) [H00028984-M01] - Analysis of monoclonal antibody to C13orf15 on HeLa cell. Antibody concentration 10 ug/ml.

RGC32 Polyclonal Antibody - bs-9079R from Bioss

Prices	$279.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

$Formalin-fixed and paraffin embedded rat brain labeled with Anti-RGC32 Polyclonal Antibody, Unconjugated (bs-9079R) at 1:200 followed by conjugation to the secondary antibody and DAB staining\\n$

Anti-RGCC antibody produced in rabbit - HPA035638 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-C13orf15: <B>Cat. No. HPA035638</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.

Anti-C13orf15 (41-55) antibody produced in rabbit - SAB1101620 from Sigma-Aldrich

Prices	$328.50
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunofluorescence</B><BR/>Anti-C13orf15 (41-55) (RB): <B>Cat. No. SAB1101620</B>: Immunofluorescence of HUVEC cells using Anti-C13orf15 (41-55) (RB) at a 1:400 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Monoclonal Anti-C13orf15 antibody produced in mouse - SAB1401655 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3B9

<B>Immunofluorescence</B><BR/>Monoclonal Anti-C13orf15: <B>Cat. No. SAB1401655</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-C13orf15 (86-100) antibody produced in rabbit - SAB1101621 from Sigma-Aldrich

Prices	$328.50
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunofluorescence</B><BR/>Anti-C13orf15 (86-100) (RB): <B>Cat. No. SAB1101621</B>: Immunofluorescence of HUVEC cells using Anti-C13orf15 (86-100) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

RGCC Antibody - middle region (ARP75541_P050) - ARP75541_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

RGC32 antibody - H00028984-M01 from Acris Antibodies

Prices	$360.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3B9

RGC32 antibody - 19556-1-AP from Proteintech Group

Host	Rabbit
Clonality	Polyclonal

Monoclonal Antibody to Response Gene To Complement 32 (RGC32) - MAN557Hu21 from Uscn Life Science Inc.

Host	Mouse
Clonality	Monoclonal

Polyclonal Antibody to Response Gene To Complement 32 (RGC32) - PAN557Hu01 from Uscn Life Science Inc.

Host	Rabbit
Clonality	Polyclonal

Anti-C13ORF15 monoclonal antibody - DCABH-10780 from Creative Diagnostics

Host	Rabbit
Clonality	Monoclonal

Anti-chromosome 13 open reading frame 15 - 08A028984 from MP Biomedicals

Prices	$456.30
Sizes	100 μg
Host	Mouse
Clonality	Monoclonal
Clone	3B9

PCRP-RGCC-2C4 - PCRP-RGCC-2C4 from Developmental Studies Hybridoma Bank

Host	Mouse
Clonality	Monoclonal

Monoclonal Antibody to Response Gene To Complement 32 (RGC32) - MAN557Hu21 from Cloud-clone

Host	Mouse
Clonality	Monoclonal

Polyclonal Antibody to Response Gene To Complement 32 (RGC32) - PAN557Hu01 from Cloud-clone

Host	Rabbit
Clonality	Polyclonal

Anti-RGCC Antibody (clone R226.1.2C4) - LS-C349545 from LifeSpan Bioscience

Prices	$195.00
Sizes	1 ml
Host	Mouse
Clonality	Monoclonal
Clone	R226.1.2C4

RGC32 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-9079R-A350 from Bioss

Prices	$379.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

RGC32 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-9079R-A488 from Bioss

Prices	$379.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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