MPST

Gene Symbol MPST
Entrez Gene 4357
Alt Symbol MST, TST2, TUM1
Species Human
Gene Type protein-coding
Description mercaptopyruvate sulfurtransferase
Other Description 3-mercaptopyruvate sulfurtransferase|human liver rhodanese|tRNA thiouridin modification protein 1
Swissprots O75750 B3KP52 P25325 J3KPV7 Q6FHN9 A8MZ34
Accessions ABB16334 ABB16335 ABB16336 EAW60133 EAW60134 EAW60135 P25325 AB208824 BAD92061 AK055733 BAG51564 AW778940 BC003508 AAH03508 BC009450 BC016737 AAH16737 BC018717 AAH18717 BI463699 BI597227 BQ072744 BT019636 AAV38442 BX406051 CR456523 CAG30409 CR541712 CAG46513 CU013123 CAK54554 CU013411 CAK54853 CX866643 CX872464 DB450861 X59434 CAA42060 XM_005261610 XP_005261667 XM_011530195 XP_011528497 XM_011530196 XP_011528498 NM_001013436 NP_001013454 NM_001130517 NP_001123989 NM_021126 NP_066949 NM_001013440 NR_024038
Function Transfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Detoxifies cyanide and is required for thiosulfate biosynthesis. Acts as an antioxidant. In combination with cysteine aminotransferase (CAT), contributes to the catabolism of cysteine and is an important producer of hydrogen sulfide in the brain, retina and vascular endothelial cells. Hydrogen sulfide H(2)S is an important synaptic modulator, signaling molecule, smooth muscle contractor and neuroprotectant. Its production by the 3MST/CAT pathway is regulated by calcium ions (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}.
Top Pathways Sulfur metabolism, Cysteine and methionine metabolism, Sulfur relay system

MPST (D-8) - sc-374326 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MPST (D-8): sc-374326. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

MPST (H-49) - sc-292174 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MPST (H-49): sc-292174. Western blot analysis of MPST expression in HEK293 (A) and HeLa (B) whole cell lysates.

MPST (H-11) - sc-376168 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MPST (H-11): sc-376168. Western blot analysis of MPST expression in HeLa (A) and Hep G2 (B) whole cell lysates.

MPST (C-12) - sc-86168 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

MPST (L-13) - sc-86170 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
MPST (L-13): sc-86170. Western blot analysis of MPST expression in non-transfected: sc-117752 (A) and mouse MPST transfected: sc-121736 (B) 293T whole cell lysates.

Anti-MPST antibody - ab70201 from Abcam

Host Mouse
Clonality Polyclonal
Anti-MPST antibody (ab70201) at 1/500 dilution + human liver tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-MPST antibody - C-terminal - ab85211 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MPST antibody - C-terminal (ab85211) at 1/50 dilutionLane 1 : HepG2 cell lysateLane 2 : HeLa cell lysateLysates/proteins at 35 µg per lane.

Anti-MPST antibody - C-terminal - ab154514 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded CL1-5 xenograft labeling MPST with ab154514 at 1/100.

Anti-MPST antibody - N-terminal - ab85377 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MPST antibody - N-terminal (ab85377) at 1/50 dilution + HeLa cell at 35 µg

Anti-MPST Antibody - LS-C309050 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MPST Antibody (aa68-278, FITC) - LS-C304524 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPST Antibody (aa68-278, Biotin) - LS-C300164 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPST Antibody (aa179-228) - LS-C111175 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MPST antibody LS-C111175 Western blot of HepG2 cell lysate.

Anti-MPST Antibody (aa68-278) - LS-C295348 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant MPST.

Anti-MPST Antibody (clone 1B5) - LS-C197700 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B5
Immunoprecipitation of MPST transfected lysate using anti-MPST monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with MPST rabbit polyclonal antibody.

Anti-MPST Antibody (aa269-297) - LS-C97555 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of MPST antibody in mouse liver tissue lysates (35 ug/lane). MPST (arrow) was detected using the purified antibody.

Anti-MPST Antibody (aa24-53) - LS-C97554 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from HepG2 cell line, using MPST Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

MPST Antibody - NBP1-82617 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MPST Antibody [NBP1-82617] - Analysis in human cell line HepG2.

MPST Antibody - NBP1-31115 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MPST Antibody [NBP1-31115] - Sample(30 ug of whole cell lysate) A:A431 12% SDS PAGEdiluted at 1:500

MPST Antibody - NBP1-54734 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MPST Antibody [NBP1-54734] - Lane 1 : 40 ug Human Liver lysate Lane 2: 40 ug Mouse Liver lysate Lane 3: 40 ug Rat Liver lysate Primary, Antibody Dilution: 1 : 1000 Secondary Antibody: Anti-rabbit Secondary Antibody conjugated with Alexa Fluor 647 Secondary, Antibody Dilution: 1 : 2500.

MPST Antibody - H00004357-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: MPST Antibody [H00004357-B01P] - Analysis of MPST expression in human liver.

MPST Antibody - H00004357-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MPST Antibody [H00004357-D01P] - Analysis of MPST expression in mouse testis.

MPST Antibody (1B5) - H00004357-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B5
Sandwich ELISA: MPST Antibody (1B5) [H00004357-M01] - Detection limit for recombinant GST tagged MPST is 0.1 ng/ml as a capture antibody.

Anti-MPST antibody produced in rabbit - SAB2103980 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MPST, antibody produced in rabbit: <B>Cat. No. SAB2103980</B>: Immunoblotting analysis of MPST in HepG2 cell lysate with MPST anitbody at 1 μg/mL.

Monoclonal Anti-MPST antibody produced in mouse - SAB1401250 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B5
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