PEX19

Gene Symbol	PEX19
Entrez Gene	5824
Alt Symbol	D1S2223E, HK33, PBD12A, PMP1, PMPI, PXF, PXMP1
Species	Human
Gene Type	protein-coding
Description	peroxisomal biogenesis factor 19
Other Description	33 kDa housekeeping protein|housekeeping gene, 33kD|peroxin-19|peroxisomal farnesylated protein
Swissprots	D3DVE7 P40855 Q8NI97 Q5QNY4
Accessions	CAA70257 EAW52727 EAW52728 EAW52729 P40855 AB018541 BAA76291 AB062286 BAB93469 AK300368 BAH13271 AK303099 BAH13899 AY434724 BC000496 AAH00496 BC064979 BT006879 AAP35525 CB993363 CD557913 DC400252 DC405033 DQ891417 ABM82343 DQ894591 ABM85517 X75535 CAA53225 NM_001193644 NP_001180573 NM_002857 NP_002848 NR_036492 NR_036493 NM_001131039
Function	Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. {ECO:0000269|PubMed:10051604, ECO:0000269|PubMed:10704444, ECO:0000269|PubMed:11259404, ECO:0000269|PubMed:11883941, ECO:0000269|PubMed:14709540, ECO:0000269|PubMed:15007061}.
Subcellular Location	Cytoplasm. Peroxisome membrane; Lipid- anchor; Cytoplasmic side. Note=Mainly cytoplasmic. Some fraction membrane-associated to the outer surface of peroxisomes.
Tissue Specificity	Ubiquitously expressed. Isoform 1 is strongly predominant in all tissues except in utero where isoform 2 is the main form. {ECO:0000269|PubMed:9339377}.
Top Pathways	Peroxisome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Peroxin 19 (C-19) - sc-18791 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Peroxin 19 (32) - sc-136029 from Santa Cruz Biotechnology Prices $279.00 Sizes 50 µg/0.5 ml Host Mouse Clonality Monoclonal

Anti-PEX19 antibody - ab95959 from Abcam Prices $384.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 antibody - ab17540 from Abcam Prices $378.00 Sizes 50 µg Host Chicken Clonality Polyclonal

Anti-PEX19 antibody - ab88365 from Abcam Prices $376.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-PEX19 antibody - ab123315 from Abcam Prices $376.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 antibody - ab116358 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 antibody [EPR9266(B)] - ab137072 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR9266(B)

Anti-PEX19 antibody [GT533] - ab184517 from Abcam Prices $376.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone GT533

Anti-PEX19 antibody [GT554] - ab184535 from Abcam Prices $376.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone GT554

Anti-PEX19 Antibody (aa1-299) - LS-C90083 from LifeSpan Bioscience Prices $665.00 Sizes 50 µg Host Chicken Clonality Polyclonal

Anti-PEX19 Antibody (Glu249) - LS-C192121 from LifeSpan Bioscience Prices $345.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (aa33-61, AP) - LS-C266077 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (aa33-61, APC) - LS-C266078 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (aa33-61, Biotin) - LS-C266079 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (aa33-61, FITC) - LS-C266080 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (aa200-249) - LS-C200483 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (aa33-61, Azide-free, HRP) - LS-C266081 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (C-Terminus, AP) - LS-C280778 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (C-Terminus, APC) - LS-C280779 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (aa33-61, PE) - LS-C266082 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (C-Terminus) - LS-C145565 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (C-Terminus, Biotin) - LS-C280780 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (C-Terminus, FITC) - LS-C280781 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PEX19 Antibody (aa32-61) - LS-C323946 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Search more