Gene Symbol | DEFA4 |
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Entrez Gene | 1669 |
Alt Symbol | DEF4, HNP-4, HP-4, HP4 |
Species | Human |
Gene Type | protein-coding |
Description | defensin, alpha 4, corticostatin |
Other Description | corticostatin|defensin, alpha 4, preproprotein|neutrophil defensin 4 |
Swissprots | Q6EZF8 P12838 |
Accessions | AAA64488 AAT68877 CAM91151 EAW80486 P12838 BC093959 AAH93959 BC106747 AAI06748 BC112091 AAI12092 BU616655 DN998607 X65977 CAA46792 NM_001925 NP_001916 |
Function | Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production. {ECO:0000269|PubMed:15616305, ECO:0000269|PubMed:15620707}. |
Subcellular Location | Secreted. |
α-defensin 4 (H-51) - sc-50344 from Santa Cruz Biotechnology
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α-defensin 4 (K-14) - sc-25871 from Santa Cruz Biotechnology
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Anti-Neutrophil defensin 4 antibody - ab135843 from Abcam
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Anti-Neutrophil defensin 4 antibody - N-terminal - ab192765 from Abcam
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Anti-HNP-4 / DEFA4 Antibody (aa27-76) IHC-plus⢠- LS-B11415 from LifeSpan Bioscience
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Anti-HNP-4 / DEFA4 Antibody (aa23-97) - LS-C314975 from LifeSpan Bioscience
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Anti-HNP-4 / DEFA4 Antibody (Asp27) IHC-plus⢠- LS-B10913 from LifeSpan Bioscience
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Anti-HNP-4 / DEFA4 Antibody (C-Terminus) - LS-C37783 from LifeSpan Bioscience
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Anti-HNP-4 / DEFA4 Antibody (C-Terminus) - LS-C37784 from LifeSpan Bioscience
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Defensin alpha 4 Antibody - NBP2-13910 from Novus Biologicals
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Defensin alpha 4 Antibody - NBP1-19770 from Novus Biologicals
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Defensin alpha 4 Polyclonal Antibody - bs-2799R from Bioss
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Anti-DEFA4 antibody produced in rabbit - SAB4301074 from Sigma-Aldrich
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Anti-DEFA4 antibody produced in rabbit - HPA051266 from Sigma-Aldrich
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Defensin Alpha4 Antibody (OAAF05722) - OAAF05722 from Aviva Systems Biology
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Anti -Defensin alpha4 (Neutrophil Defensin 4, Defensin, alpha 4, HNP-4, HP-4, DEFA4, DEF4,alpha-Defensin 4) - 222137 from USBiological Life Science
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Defensin alpha 4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-2799R-A350 from Bioss
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Defensin alpha 4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-2799R-A488 from Bioss
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Defensin alpha 4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-2799R-A555 from Bioss
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Defensin alpha 4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-2799R-A647 from Bioss
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Defensin alpha 4 Polyclonal Antibody, Cy3 Conjugated - bs-2799R-Cy3 from Bioss
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Defensin alpha 4 Polyclonal Antibody, Cy5 Conjugated - bs-2799R-Cy5 from Bioss
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Defensin alpha 4 Polyclonal Antibody, Cy5.5 Conjugated - bs-2799R-Cy5.5 from Bioss
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Defensin alpha 4 Polyclonal Antibody, Cy7 Conjugated - bs-2799R-Cy7 from Bioss
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Defensin alpha 4 Polyclonal Antibody, FITC Conjugated - bs-2799R-FITC from Bioss
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