| Gene Symbol |
DEFA4
|
| Entrez Gene |
1669
|
| Alt Symbol |
DEF4, HNP-4, HP-4, HP4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
defensin, alpha 4, corticostatin
|
| Other Description |
corticostatin|defensin, alpha 4, preproprotein|neutrophil defensin 4
|
| Swissprots |
Q6EZF8 P12838
|
| Accessions |
AAA64488 AAT68877 CAM91151 EAW80486 P12838 BC093959 AAH93959 BC106747 AAI06748 BC112091 AAI12092 BU616655 DN998607 X65977 CAA46792 NM_001925 NP_001916
|
| Function |
Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production. {ECO:0000269|PubMed:15616305, ECO:0000269|PubMed:15620707}.
|
| Subcellular Location |
Secreted.
|