SCNN1G

Gene Symbol SCNN1G
Entrez Gene 6340
Alt Symbol BESC3, ENaCg, ENaCgamma, PHA1, SCNEG
Species Human
Gene Type protein-coding
Description sodium channel, non voltage gated 1 gamma subunit
Other Description ENaC gamma subunit|amiloride-sensitive epithelial sodium channel gamma subunit|amiloride-sensitive sodium channel gamma-subunit|amiloride-sensitive sodium channel subunit gamma|epithelial Na(+) channel subunit gamma|gamma-ENaC|gamma-NaCH|nonvoltage-gated sodium channel 1 subunit gamma|sodium channel, non-voltage-gated 1, gamma subunit|sodium channel, nonvoltage-gated 1, gamma
Swissprots Q96TD2 Q93026 Q93027 P51170 Q6PCC2 P78437 Q93024 Q93025 Q93023
Accessions AAC50217 AAC50744 AAC50745 AAC50746 AAC50747 AAC50748 AAC50749 AAC50750 AAC50751 AAC50752 AAC50753 AAC50754 AAC50755 AAC50756 AAC50757 AAC50758 AAC50759 AAC50760 AAC50761 AAK50910 ACS13725 CAB07506 EAW55837 EAW55838 P51170 BC059391 AAH59391 BC069652 AAH69652 DQ402524 ABD72220 L36592 AAA75460 U48936 AAC50737 X87160 CAA60633 NM_001039 NP_001030
Function Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. {ECO:0000269|PubMed:24124190}.
Subcellular Location Apical cell membrane {ECO:0000269|PubMed:24124190}; Multi-pass membrane protein {ECO:0000269|PubMed:24124190}. Note=Apical membrane of epithelial cells.
Tissue Specificity Expressed in kidney (at protein level). {ECO:0000269|PubMed:22207244}.
Top Pathways Taste transduction, Aldosterone-regulated sodium reabsorption

γENaC (F-20) - sc-22245 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
γENaC (F-20): sc-22245. Western blot analysis of γENaC expression in A549 (A), Caki-1 (B), NCI-H1688 (C) and COLO 320DM (D) whole cell lysates.

γENaC (H-110) - sc-21014 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
γENaC (H-110): sc-21014. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing membrane and cytoplasmic staining of cells in glomeruli and cytoplasmic staining of cells in tubules.

Anti-epithelial Sodium Channel gamma antibody - ab3468 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-epithelial Sodium Channel gamma antibody (ab3468) at 1/2000 dilutionLane 1 : H441 whole cell lysate (treated with dexamethasone)Lane 2 : H441 whole cell lysate (treated with dexamethasone) with Immunizing peptideLysates/proteins at 50 µg per lane.SecondaryHRP conjugated donkey anti-rabbitdeveloped using the ECL techniquePerformed under reducing conditions.Observed band size : 90-95 kDa (why is the actual band size different from the predicted?)Additional bands at : 50 kDa (possible non-specific binding).Exposure time : 15 secondsThis image is courtesy of an anonymous AbreviewSee Abreview

Anti-epithelial Sodium Channel gamma antibody - ab65707 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-epithelial Sodium Channel gamma antibody - ab133430 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-epithelial Sodium Channel gamma antibody (ab133430) at 1 µg/mlLane 1 : A498 (Human Kidney Carcinoma) Whole Cell LysateLane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLane 3 : WI38 (Human lung fibroblast cell line) Whole Cell Lysate (ab3960)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-epithelial Sodium Channel gamma antibody - ab135280 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-epithelial Sodium Channel gamma antibody (ab135280) at 1/500 dilution + Extracts from A549 cells at 30 µg

Anti-epithelial Sodium Channel gamma antibody - ab115272 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Human colon (formalin fixed, paraffin embedded) tissue stained with ab115272 at 4 µg/ml by Immunohistochemistry. After incubation with the primary antibody, slides were incubated with biotinylated anti-goat IgG secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Anti-epithelial Sodium Channel gamma antibody - Carboxyterminal end - ab56163 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (C-Terminus) IHC-plus™ - LS-B2609 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SCNN1G antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2609 concentration 5 ug/ml.

Anti-SCNN1G / ENaC Gamma Antibody (N-Terminus) - LS-C23197 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (N-Terminus) - LS-C23198 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (N-Terminus) - LS-C23199 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (C-Terminus) - LS-C124569 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, Atto 565) - LS-C229768 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, Atto 594) - LS-C229770 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, Atto 633) - LS-C229769 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, Atto 655) - LS-C229771 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, Atto 680) - LS-C229772 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, Atto 700) - LS-C229773 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, AP) - LS-C229774 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, APC) - LS-C229775 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, Biotin) - LS-C229776 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, FITC) - LS-C229777 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (aa629-650, PE, Atto 594) - LS-C229779 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SCNN1G / ENaC Gamma Antibody (clone 2F3) - LS-C198156 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F3
Detection limit for recombinant GST tagged SCNN1G is 1 ng/ml as a capture antibody.
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