SCNN1G

Gene Symbol SCNN1G
Entrez Gene 6340
Alt Symbol BESC3, ENaCg, ENaCgamma, PHA1, SCNEG
Species Human
Gene Type protein-coding
Description sodium channel, non voltage gated 1 gamma subunit
Other Description ENaC gamma subunit|amiloride-sensitive epithelial sodium channel gamma subunit|amiloride-sensitive sodium channel gamma-subunit|amiloride-sensitive sodium channel subunit gamma|epithelial Na(+) channel subunit gamma|gamma-ENaC|gamma-NaCH|nonvoltage-gated sodium channel 1 subunit gamma|sodium channel, non-voltage-gated 1, gamma subunit|sodium channel, nonvoltage-gated 1, gamma
Swissprots Q96TD2 Q93026 Q93027 P51170 Q6PCC2 P78437 Q93024 Q93025 Q93023
Accessions AAC50217 AAC50744 AAC50745 AAC50746 AAC50747 AAC50748 AAC50749 AAC50750 AAC50751 AAC50752 AAC50753 AAC50754 AAC50755 AAC50756 AAC50757 AAC50758 AAC50759 AAC50760 AAC50761 AAK50910 ACS13725 CAB07506 EAW55837 EAW55838 P51170 BC059391 AAH59391 BC069652 AAH69652 DQ402524 ABD72220 L36592 AAA75460 U48936 AAC50737 X87160 CAA60633 NM_001039 NP_001030
Function Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. {ECO:0000269|PubMed:24124190}.
Subcellular Location Apical cell membrane {ECO:0000269|PubMed:24124190}; Multi-pass membrane protein {ECO:0000269|PubMed:24124190}. Note=Apical membrane of epithelial cells.
Tissue Specificity Expressed in kidney (at protein level). {ECO:0000269|PubMed:22207244}.
Top Pathways Taste transduction, Aldosterone-regulated sodium reabsorption

γENaC CRISPR/Cas9 KO Plasmid (h) - sc-402577 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

γENaC HDR Plasmid (h) - sc-402577-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

γENaC Double Nickase Plasmid (h) - sc-402577-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

γENaC Double Nickase Plasmid (h2) - sc-402577-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

γENaC CRISPR Activation Plasmid (h) - sc-402577-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

γENaC CRISPR Activation Plasmid (h2) - sc-402577-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

γENaC Lentiviral Activation Particles (h) - sc-402577-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

γENaC Lentiviral Activation Particles (h2) - sc-402577-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

γENaC siRNA (h) - sc-42419 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

γENaC shRNA Plasmid (h) - sc-42419-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

γENaC shRNA (h) Lentiviral Particles - sc-42419-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

epithelial Sodium Channel gamma RNAi - H00006340-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU022951 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1880 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1880 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09268 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09268

SCNN1G siRNA (Human) - CRH4275 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SCNN1G - MBS8208934 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human SCNN1G siRNA - orb264777 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SCNN1G shRNA Plasmid (Human) - CHH4275 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SCNN1G miRNA 3'UTR clone - MiUTR3H-03613 from Creative biogene

Species Reactivities Human
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