PIDD1

Gene Symbol	PIDD1
Entrez Gene	55367
Alt Symbol	LRDD, PIDD
Species	Human
Gene Type	protein-coding
Description	p53-induced death domain protein 1
Other Description	leucine-rich repeat and death domain-containing protein|leucine-rich repeats and death domain containing|p53-induced death domain-containing protein 1|p53-induced protein with a death domain
Swissprots	Q8NDL2 Q8NC89 Q59HC7 Q59H10 Q9NRE6 Q9HB75 Q59FD1 Q7Z4P8 Q96C25
Accessions	CCQ43600 EAX02390 EAX02391 EAX02392 Q9HB75 AB208832 BAD92069 AB208949 BAD92186 AB209529 BAD92766 AF229178 AAF69491 AF274972 AAG13461 AF465246 AAP97716 AK074893 BAC11272 AL833849 CAD38708 BC014904 AAH14904 BG723687 BQ059356 BQ214414 BQ924290 BX349115 CN427944 CN427946 EU176211 ABW03662 XM_005253005 XP_005253062 XM_005253006 XP_005253063 XM_005253007 XP_005253064 XM_005253008 XP_005253065 XM_011520209 XP_011518511 XM_011520210 XP_011518512 XM_011520211 XP_011518513 XM_011520212 XP_011518514 XM_011520213 XP_011518515 XR_930877 NM_145886 NP_665893 NM_145887 NP_665894 NM_018494
Function	Promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. Associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which an important regulator in apoptotic pathways. {ECO:0000269|PubMed:10973264, ECO:0000269|PubMed:15073321, ECO:0000269|PubMed:16360037}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16360037}. Nucleus {ECO:0000269|PubMed:16360037}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:10825539}.
Top Pathways	p53 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LRDD peptide - ab87817 from Abcam Category Peptide

PIDD1 Antibody Blocking Peptide - LS-E20897 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PIDD1 Antibody Blocking Peptide - LS-E20898 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LRDD-Antibody-C-term-Blocking-peptide - BP13884b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LRDD Blocking Peptide - 33R-8131 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LRDD Blocking Peptide - 33R-8046 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LRDD fusion protein - Ag2761 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human p53-induced protein with a death domain(PIDD) ,partial - CSB-YP888017HU CSB-EP888017HU CSB-BP888017HU CSB-MP888017HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

LRDD Protein - abx164961 from Abbexa Category Protein Species Human, Mouse, Rat

Recombinant Leucine Rich Repeats And Death Domain Containing Protein (LRDD) - RPC572Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Leucine Rich Repeats And Death Domain Containing Protein (LRDD) - RPC572Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Leucine Rich Repeats And Death Domain Containing Protein (LRDD) - RPC572Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

p53-induced protein with a death domain (PIDD), partial, Recombinant Protein - MBS1290739 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Leucine Rich Repeats And Death Domain Containing Protein (LRDD) - RPC572Hu01 from Cloud-clone Category Protein Source E.coli Species Human

PIDD Peptide, Human - M34GP11749H from Creative Peptides Category Peptide Source Synthetic. Species Human

PIDD1 Recombinant Protein (OPCD00719) - OPCD00719 from Aviva Systems Biology Category Protein Source E.coli Species Human

LRDD Recombinant Protein Antigen - NBP2-56216PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Leucine Rich Repeats And Death Domain Containing Protein, Recombinant Protein - MBS2032921 from MyBioSource Category Protein Prices $170.00, $350.00, $540.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Leucine Rich Repeats And Death Domain Containing Protein, Recombinant Protein - MBS2033068 from MyBioSource Category Protein Prices $185.00, $385.00, $595.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

Leucine Rich Repeats And Death Domain Containing Protein, Recombinant Protein - MBS2033625 from MyBioSource Category Protein Prices $185.00, $380.00, $585.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

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